AutismKB 2.0

Annotation Details for CRTC2


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Basic Information Top
Gene Symbol:CRTC2 ( TORC2 )
Gene Full Name: CREB regulated transcription coactivator 2
Band: 1q21.3
Quick LinksEntrez ID:200186; OMIM: 608972; Uniprot ID:CRTC2_HUMAN; ENSEMBL ID: ENSG00000160741; HGNC ID: 27301
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005737ISS-cytoplasm-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0005515IPI-protein binding19164291
GO:0008140IBA-cAMP response element binding protein binding-
GO ID Evidence Qualifier GO_term References
GO:0006094ISS-gluconeogenesis-
GO:0006351IEA-transcription, DNA-templated-
GO:0016032IEA-viral process-
GO:0032793IBA-positive regulation of CREB transcription factor activity-
GO:0032793ISS-positive regulation of CREB transcription factor activity-
GO:0042593ISS-glucose homeostasis-
GO:0043970IEA-histone H3-K9 acetylation-
GO:0045944IBA-positive regulation of transcription from RNA polymerase II promoter-
GO:0051289IEA-protein homotetramerization-
GO:1901998IEA-toxin transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CRTC2UBC12830817805301 Affinity Capture-Western
CRTC2UBC11316417805301 Affinity Capture-Western
CRTC2YWHAG12830817353931 Affinity Capture-MS
CRTC2YWHAG11336417353931 Affinity Capture-MS
CRTC2HIST1H3B12830819279000 Affinity Capture-Western
CRTC2HIST1H3B11395419279000 Affinity Capture-Western
CRTC2YWHAQ12830815454081 17353931 Affinity Capture-MS; Affinity Capture-Western
CRTC2YWHAQ11616815454081 17353931 Affinity Capture-MS; Affinity Capture-Western
CRTC2SIK211684015454081 Affinity Capture-Western; Biochemical Activity
CRTC2SIK212830815454081 Affinity Capture-Western; Biochemical Activity
CRTC2RFWD212830817805301 Affinity Capture-Western
CRTC2RFWD212213617805301 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1921593
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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