AutismKB 2.0

Annotation Details for ELK1


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Basic Information Top
Gene Symbol:ELK1 ( - )
Gene Full Name: ELK1, member of ETS oncogene family
Band: Xp11.23
Quick LinksEntrez ID:2002; OMIM: 311040; Uniprot ID:ELK1_HUMAN; ENSEMBL ID: ENSG00000126767; HGNC ID: 3321
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IC-nucleus14970218
GO:0005634IDA-nucleus20018936
GO:0005654IDA-nucleoplasm-
GO:0005739IEA-mitochondrion-
GO:0030425IEA-dendrite-
GO:0043025IEA-neuronal cell body-
GO:0043679IEA-axon terminus-
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding12750007
GO:0001047IEA-core promoter binding-
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding12750007
GO:0001085IPI-RNA polymerase II transcription factor binding26612202
GO:0003682IEA-chromatin binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding14970218
GO:0005515IPI-protein binding16291755
GO ID Evidence Qualifier GO_term References
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0009416IEA-response to light stimulus-
GO:0030154IBA-cell differentiation-
GO:0045893IDA-positive regulation of transcription, DNA-templated15790681
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter12750007
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter22065586
GO:0071394IEA-cellular response to testosterone stimulus-
GO:0071480IEA-cellular response to gamma radiation-
GO:0071774ISS-response to fibroblast growth factor-
GO:1901216IEA-positive regulation of neuron death-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAPK8ELK11115858586671 Biochemical Activity
MAPK8ELK11083178586671 Biochemical Activity
MAPK1ELK11115808586671 10644696 12594221 Biochemical Activity; Reconstituted Complex
MAPK1ELK11083178586671 10644696 12594221 Biochemical Activity; Reconstituted Complex
EWSR1ELK11084319010223 Reconstituted Complex
EWSR1ELK11083179010223 Reconstituted Complex
FLI1ELK11086029010223 Reconstituted Complex
FLI1ELK11083179010223 Reconstituted Complex
SRFELK11126009010223 Reconstituted Complex
SRFELK11083179010223 Reconstituted Complex
STK16ELK111414410947953 Biochemical Activity
STK16ELK110831710947953 Biochemical Activity
HDAC1ELK110831711283259 Reconstituted Complex
HDAC1ELK110931511283259 Reconstituted Complex
EP300ELK110834712514134 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
EP300ELK110831712514134 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
KLF4ELK111472618768922 Affinity Capture-Western
KLF4ELK110831718768922 Affinity Capture-Western
HOXB13ELK111574420211142 Two-hybrid
HOXB13ELK110831720211142 Two-hybrid
EMX1ELK110833120211142 Two-hybrid
EMX1ELK110831720211142 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
ELK1MAPK141959299130707 Elk-1 is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Elk-1 and p38 MAPK from an unspecified species.
ELK1MAPK141948149155018 An unspecified isoform of p38 interacts with and phosphorylates Elk-1.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101833
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090529-5'