AutismKB 2.0

Annotation Details for APLF


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Basic Information Top
Gene Symbol:APLF ( APFL,C2orf13,FLJ16593,MGC47799,PALF,Xip1 )
Gene Full Name: aprataxin and PNKP like factor
Band: 2p13.3
Quick LinksEntrez ID:200558; OMIM: 611035; Uniprot ID:APLF_HUMAN; ENSEMBL ID: ENSG00000169621; HGNC ID: 28724
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17396150
GO:0005654IDA-nucleoplasm-
GO:0005829IEA-cytosol-
GO:0035861IDA-site of double-strand break21211721
GO ID Evidence Qualifier GO_term References
GO:0000166IDA-nucleotide binding18172500
GO:0003906IDA-DNA-(apurinic or apyrimidinic site) lyase activity17396150
GO:0004520IDA-endodeoxyribonuclease activity17396150
GO:0005515IPI-protein binding17353262
GO:0008408IDA-3'-5' exonuclease activity17396150
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000012IMP-single strand break repair17396150
GO:0006302IMP-double-strand break repair17396150
GO:0006974IDA-cellular response to DNA damage stimulus17396150
GO:0045191IEA-regulation of isotype switching-
GO:0051106IGI-positive regulation of DNA ligation21211721
GO:0090305IEA-nucleic acid phosphodiester bond hydrolysis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
APLFCHD1L12833419661379 Affinity Capture-Western
APLFCHD1L11492919661379 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919353
  • Data Attributes: HomoloGene calculated
No data