AutismKB 2.0

Annotation Details for PIKFYVE


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Basic Information Top
Gene Symbol:PIKFYVE ( CFD,FAB1,FLJ37746,KIAA0981,MGC40423,PIP5K,PIP5K3 )
Gene Full Name: phosphoinositide kinase, FYVE finger containing
Band: 2q34
Quick LinksEntrez ID:200576; OMIM: 609414; Uniprot ID:FYV1_HUMAN; ENSEMBL ID: ENSG00000115020; HGNC ID: 23785
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139TAS-Golgi membrane-
GO:0005829IEA-cytosol-
GO:0005911IEA-cell-cell junction-
GO:0010008IDA-endosome membrane17556371
GO:0012506IEA-vesicle membrane-
GO:0031901IDA-early endosome membrane16448788
GO:0031901TAS-early endosome membrane-
GO:0031902TAS-late endosome membrane-
GO:0045121IDA-membrane raft15046600
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000285IBA-1-phosphatidylinositol-3-phosphate 5-kinase activity-
GO:0005515IPI-protein binding15046600
GO:0005524IEA-ATP binding-
GO:0008270IEA-zinc ion binding-
GO:0016308TAS-1-phosphatidylinositol-4-phosphate 5-kinase activity15046600
GO:0043813TAS-phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity-
GO:0044183IBANOTprotein binding involved in protein folding-
GO:0051082IBANOTunfolded protein binding-
GO ID Evidence Qualifier GO_term References
GO:0006458IBANOT'de novo' protein folding-
GO:0006661TAS-phosphatidylinositol biosynthetic process-
GO:0006898IMPNOTreceptor-mediated endocytosis14551253
GO:0032288IEA-myelin assembly-
GO:0034504IMP-protein localization to nucleus17909029
GO:0035556IEA-intracellular signal transduction-
GO:0036092IEA-phosphatidylinositol-3-phosphate biosynthetic process-
GO:0042147IMP-retrograde transport, endosome to Golgi14551253
GO:0046854IEA-phosphatidylinositol phosphorylation-
GO:0061077IBANOTchaperone-mediated protein folding-
GO:1904562IC-phosphatidylinositol 5-phosphate metabolic process25578879
GO:2000785IMP-regulation of autophagosome assembly25578879
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PIKFYVERABEPK11553814530284 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
PIKFYVERABEPK12833614530284 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
PIKFYVEVAC1412833619037259 Two-hybrid
PIKFYVEVAC1412082219037259 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1335106
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9636'