AutismKB 2.0

Annotation Details for SPRED2


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Basic Information Top
Gene Symbol:SPRED2 ( FLJ21897,FLJ31917,MGC163164,Spred-2 )
Gene Full Name: sprouty-related, EVH1 domain containing 2
Band: 2p14
Quick LinksEntrez ID:200734; OMIM: 609292; Uniprot ID:SPRE2_HUMAN; ENSEMBL ID: ENSG00000198369; HGNC ID: 17722
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO:0030658IEA-transport vesicle membrane-
GO ID Evidence Qualifier GO_term References
GO:0005173ISS-stem cell factor receptor binding-
GO:0005515IPI-protein binding19822672
GO:0019901IPI-protein kinase binding20736167
GO:0030291ISS-protein serine/threonine kinase inhibitor activity20736167
GO ID Evidence Qualifier GO_term References
GO:0000188ISS-inactivation of MAPK activity-
GO:0007275IEA-multicellular organism development-
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0010801IMP-negative regulation of peptidyl-threonine phosphorylation20736167
GO:0043517ISS-positive regulation of DNA damage response, signal transduction by p53 class mediator20736167
GO:0090311ISS-regulation of protein deacetylation20736167
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SPRED2TESK111287517974561 Affinity Capture-Western
SPRED2TESK112834417974561 Affinity Capture-Western
SPRED2UBC12834417094949 Affinity Capture-Western
SPRED2UBC11316417094949 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2150019
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2342'