AutismKB 2.0

Annotation Details for MARK2


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Basic Information Top
Gene Symbol:MARK2 ( EMK-1,EMK1,MGC99619,PAR-1,Par1b )
Gene Full Name: MAP/microtubule affinity-regulating kinase 2
Band: 11q13.1
Quick LinksEntrez ID:2011; OMIM: 600526; Uniprot ID:MARK2_HUMAN; ENSEMBL ID: ENSG00000072518; HGNC ID: 3332
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005739NAS-mitochondrion24522549
GO:0005884IDA-actin filament23902687
GO:0005886IDA-plasma membrane23902687
GO:0016020IMP-membrane14976552
GO:0016328IDA-lateral plasma membrane23902687
GO:0097427IDA-microtubule bundle23902687
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding14976552
GO:0003723IDA-RNA binding22658674
GO:0004674IDA-protein serine/threonine kinase activity14976552
GO:0004674NAS-protein serine/threonine kinase activity8274451
GO:0004674TAS-protein serine/threonine kinase activity24522549
GO:0005515IPI-protein binding14676191
GO:0005524IDA-ATP binding14976552
GO:0008289IEA-lipid binding-
GO:0030295TAS-protein kinase activator activity24522549
GO:0045296IDA-cadherin binding25468996
GO:0050321ISS-tau-protein kinase activity-
GO ID Evidence Qualifier GO_term References
GO:0000226IEA-microtubule cytoskeleton organization-
GO:0000422NAS-mitophagy24522549
GO:0001764ISS-neuron migration-
GO:0006468IDA-protein phosphorylation14976552
GO:0006468NAS-protein phosphorylation8274451
GO:0010976IDA-positive regulation of neuron projection development12429843
GO:0016055IEA-Wnt signaling pathway-
GO:0018107TAS-peptidyl-threonine phosphorylation24522549
GO:0030010IDA-establishment of cell polarity12429843
GO:0030010TAS-establishment of cell polarity16775013
GO:0032147TAS-activation of protein kinase activity24522549
GO:0035556IDA-intracellular signal transduction14976552
GO:0045197IDA-establishment or maintenance of epithelial cell apical/basal polarity15324659
GO:0046777ISS-protein autophosphorylation-
GO:0050770IMP-regulation of axonogenesis20194617
GO:0051493ISS-regulation of cytoskeleton organization-
GO:0051646NAS-mitochondrion localization24522549
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MARK2AKT110671018292230 Affinity Capture-Western
MARK2AKT110832618292230 Affinity Capture-Western
MARK2DTNA10832619615732 Affinity Capture-MS
MARK2DTNA10817019615732 Affinity Capture-MS
MAP3K3MARK211037914743216 Affinity Capture-MS
MAP3K3MARK210832614743216 Affinity Capture-MS
SFNMARK210907215778465 Affinity Capture-MS
SFNMARK210832615778465 Affinity Capture-MS
HDAC7MARK211961316980613 Affinity Capture-Western; Biochemical Activity
HDAC7MARK210832616980613 Affinity Capture-Western; Biochemical Activity
YWHAQMARK211616817353931 Affinity Capture-MS
YWHAQMARK210832617353931 Affinity Capture-MS
YWHAGMARK211336417353931 Affinity Capture-MS
YWHAGMARK210832617353931 Affinity Capture-MS
COL4A3BPMARK210832619615732 Affinity Capture-MS
COL4A3BPMARK211539619615732 Affinity Capture-MS
C11orf58MARK211614419615732 Affinity Capture-MS
C11orf58MARK210832619615732 Affinity Capture-MS
CLASP2MARK211674319615732 Affinity Capture-MS
CLASP2MARK210832619615732 Affinity Capture-MS
PMPCAMARK210832619615732 Affinity Capture-MS
PMPCAMARK211681119615732 Affinity Capture-MS
PHLPP1MARK211684319615732 Affinity Capture-MS
PHLPP1MARK210832619615732 Affinity Capture-MS
KIAA0802MARK211685919615732 Affinity Capture-MS
KIAA0802MARK210832619615732 Affinity Capture-MS
KIF13BMARK211689519615732 Affinity Capture-MS
KIF13BMARK210832619615732 Affinity Capture-MS
FUCA1MARK210832619615732 Affinity Capture-MS
FUCA1MARK210879319615732 Affinity Capture-MS
USP21MARK211795019615732 Affinity Capture-MS
USP21MARK210832619615732 Affinity Capture-MS
KIF5BMARK210832619615732 Affinity Capture-MS
KIF5BMARK211000019615732 Affinity Capture-MS
C6orf204MARK210832619615732 Affinity Capture-MS
C6orf204MARK213225519615732 Affinity Capture-MS
MARK1MARK211030919615732 Affinity Capture-MS
MARK1MARK210832619615732 Affinity Capture-MS
MARK3MARK211031019615732 Affinity Capture-MS
MARK3MARK210832619615732 Affinity Capture-MS
UTP18MARK211928519615732 Affinity Capture-MS
UTP18MARK210832619615732 Affinity Capture-MS
PRKCIMARK210832619615732 Affinity Capture-MS
PRKCIMARK211157019615732 Affinity Capture-MS
MARK4MARK210832619615732 Affinity Capture-MS
MARK4MARK212176019615732 Affinity Capture-MS
SNTB2MARK211252819615732 Affinity Capture-MS
SNTB2MARK210832619615732 Affinity Capture-MS
UTRNMARK210832619615732 Affinity Capture-MS
UTRNMARK211324519615732 Affinity Capture-MS
YWHAHMARK210832619615732 Affinity Capture-MS
YWHAHMARK211336519615732 Affinity Capture-MS
ARHGEF2MARK211461819615732 Affinity Capture-MS
ARHGEF2MARK210832619615732 Affinity Capture-MS
GPRASP1MARK211508619615732 Affinity Capture-MS
GPRASP1MARK210832619615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99638
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080215-4'