AutismKB 2.0

Annotation Details for ENDOG


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Basic Information Top
Gene Symbol:ENDOG ( FLJ27463 )
Gene Full Name: endonuclease G
Band: 9q34.11
Quick LinksEntrez ID:2021; OMIM: 600440; Uniprot ID:NUCG_HUMAN; ENSEMBL ID: ENSG00000167136; HGNC ID: 3346
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005739IEA-mitochondrion-
GO:0005829IEA-cytosol-
GO:0043204IEA-perikaryon-
GO ID Evidence Qualifier GO_term References
GO:0003676IEA-nucleic acid binding-
GO:0004519IEA-endonuclease activity-
GO:0004536IEA-deoxyribonuclease activity-
GO:0005515IPI-protein binding25036637
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0006309IBA-apoptotic DNA fragmentation-
GO:0006310TAS-DNA recombination18309324
GO:0007568IEA-aging-
GO:0009612IEA-response to mechanical stimulus-
GO:0032355IEA-response to estradiol-
GO:0034612IEA-response to tumor necrosis factor-
GO:0036475IEA-neuron death in response to oxidative stress-
GO:0046677IEA-response to antibiotic-
GO:0071277IEA-cellular response to calcium ion-
GO:0071333IEA-cellular response to glucose stimulus-
GO:0071456IEA-cellular response to hypoxia-
GO:1901300IEA-positive regulation of hydrogen peroxide-mediated programmed cell death-
GO:1902512IEA-positive regulation of apoptotic DNA fragmentation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FEN1ENDOG10852816133872 Affinity Capture-Western
FEN1ENDOG10833616133872 Affinity Capture-Western
AIFM1ENDOG11457916133872 Affinity Capture-Western
AIFM1ENDOG10833616133872 Affinity Capture-Western
HSPA4ENDOG10954016133872 Affinity Capture-Western; Co-purification
HSPA4ENDOG10833616133872 Affinity Capture-Western; Co-purification
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1261433
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018