AutismKB 2.0

Annotation Details for ENO1


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Basic Information Top
Gene Symbol:ENO1 ( ENO1L1,MPB1,NNE,PPH )
Gene Full Name: enolase 1, (alpha)
Band: 1p36.23
Quick LinksEntrez ID:2023; OMIM: 172430; Uniprot ID:ENOA_HUMAN; ENSEMBL ID: ENSG00000074800; HGNC ID: 3350
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000015IDA-phosphopyruvate hydratase complex3529090
GO:0005615IDA-extracellular space16502470
GO:0005634IC-nucleus2005901
GO:0005634IDA-nucleus21630459
GO:0005737IDA-cytoplasm15459207
GO:0005829IDA-cytosol12666133
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane12666133
GO:0009986IDA-cell surface12666133
GO:0016020IDA-membrane19433310
GO:0031430IEA-M band-
GO:0070062IDA-extracellular exosome11487543
GO:0099738IDA-cell cortex region19433310
GO ID Evidence Qualifier GO_term References
GO:0000287IEA-magnesium ion binding-
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding2005901
GO:0003677IEA-DNA binding-
GO:0003723IDA-RNA binding22658674
GO:0004634IMP-phosphopyruvate hydratase activity3529090
GO:0004634TAS-phosphopyruvate hydratase activity-
GO:0005515IPI-protein binding11134351
GO:0042803IDA-protein homodimerization activity3529090
GO:0045296IDA-cadherin binding25468996
GO:0051020IPI-GTPase binding24337748
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter2005901
GO:0006094TAS-gluconeogenesis-
GO:0006351IEA-transcription, DNA-templated-
GO:0009615IEP-response to virus16548883
GO:0010756IMP-positive regulation of plasminogen activation12666133
GO:0030308IDA-negative regulation of cell growth10082554
GO:0045892IDA-negative regulation of transcription, DNA-templated10082554
GO:0045892IMP-negative regulation of transcription, DNA-templated10681589
GO:0045933IGI-positive regulation of muscle contraction15459207
GO:0061621IMP-canonical glycolysis3529090
GO:0061621TAS-canonical glycolysis-
GO:1903298IDA-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway15459207
GO:1903298IGI-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway15459207
GO:2001171IDA-positive regulation of ATP biosynthetic process15459207
GO:2001171IGI-positive regulation of ATP biosynthetic process15459207
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HDAC1ENO110931510403782 Affinity Capture-Western; Reconstituted Complex
HDAC1ENO110833810403782 Affinity Capture-Western; Reconstituted Complex
TRAPPC2ENO111229911134351 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TRAPPC2ENO110833811134351 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PLGENO111135611169399 Reconstituted Complex
PLGENO110833811169399 Reconstituted Complex
FANCAENO110847214499622 Two-hybrid
FANCAENO110833814499622 Two-hybrid
MAP2K5ENO111159315805119 Affinity Capture-Western
MAP2K5ENO110833815805119 Affinity Capture-Western
ISG15ENO111499516884686 Affinity Capture-MS
ISG15ENO110833816884686 Affinity Capture-MS
SUMO2ENO111249719394292 Affinity Capture-MS
SUMO2ENO110833819394292 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
ENO1rs11811795, rs12142493, rs1325920, rs2071414, rs2765507 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95393
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6048'