AutismKB 2.0

Annotation Details for EPHA3


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Basic Information Top
Gene Symbol:EPHA3 ( EK4,ETK,ETK1,HEK,HEK4,TYRO4 )
Gene Full Name: EPH receptor A3
Band: 3p11.1
Quick LinksEntrez ID:2042; OMIM: 179611; Uniprot ID:EPHA3_HUMAN; ENSEMBL ID: ENSG00000044524; HGNC ID: 3387
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IEA-extracellular region-
GO:0005769IDA-early endosome21135139
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane11870224
GO ID Evidence Qualifier GO_term References
GO:0005004IDA-GPI-linked ephrin receptor activity11870224
GO:0005515IPI-protein binding11870224
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0007155IEA-cell adhesion-
GO:0010717ISS-regulation of epithelial to mesenchymal transition-
GO:0010976IMP-positive regulation of neuron projection development17910947
GO:0016477ISS-cell migration-
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0032956IDA-regulation of actin cytoskeleton organization11870224
GO:0043087IDA-regulation of GTPase activity11870224
GO:0048013IDA-ephrin receptor signaling pathway11870224
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0051893IDA-regulation of focal adhesion assembly11870224
GO:0070507IDA-regulation of microtubule cytoskeleton organization11870224
GO:0071300IMP-cellular response to retinoic acid17910947
GO:0097155ISS-fasciculation of sensory neuron axon-
GO:0097156ISS-fasciculation of motor neuron axon-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPHA3ABL110835611494128 Reconstituted Complex
EPHA3ABL110654311494128 Reconstituted Complex
EPHA3CRK10835611870224 Affinity Capture-Western
EPHA3CRK10778811870224 Affinity Capture-Western
EPHA3EFNA11083569195962 Reconstituted Complex
EPHA3EFNA11082629195962 Reconstituted Complex
EPHA3EFNA31083569195962 Reconstituted Complex
EPHA3EFNA31082649195962 Reconstituted Complex
EPHA3EFNA41083569195962 Reconstituted Complex
EPHA3EFNA41082659195962 Reconstituted Complex
EPHA3EFNA51083569195962 9245480 Co-fractionation; Reconstituted Complex
EPHA3EFNA51082669195962 9245480 Co-fractionation; Reconstituted Complex
EPHA3EFNB11083569195962 Reconstituted Complex
EPHA3EFNB11082679195962 Reconstituted Complex
EPHA3EFNB21083568559144 9195962 Reconstituted Complex
EPHA3EFNB21082688559144 9195962 Reconstituted Complex
FYNEPHA31083569632142 Reconstituted Complex
FYNEPHA31088109632142 Reconstituted Complex
SRCEPHA31083569632142 Reconstituted Complex
SRCEPHA31125929632142 Reconstituted Complex
TP53EPHA310835615355990 Reconstituted Complex
TP53EPHA311301015355990 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99612
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010724-10'