AutismKB 2.0

Annotation Details for EPHB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EPHB2 ( CAPB,DRT,EK5,EPHT3,ERK,Hek5,MGC87492,PCBC,Tyro5 )
Gene Full Name: EPH receptor B2
Band: 1p36.12
Quick LinksEntrez ID:2048; OMIM: 600997; Uniprot ID:EPHB2_HUMAN; ENSEMBL ID: ENSG00000133216; HGNC ID: 3393
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane-
GO:0030424ISS-axon-
GO:0030425ISS-dendrite-
GO:0098794TAS-postsynapse26224839
GO ID Evidence Qualifier GO_term References
GO:0004713ISS-protein tyrosine kinase activity-
GO:0005005ISS-transmembrane-ephrin receptor activity-
GO:0005005TAS-transmembrane-ephrin receptor activity8589679
GO:0005515IPI-protein binding17255949
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0001525ISS-angiogenesis-
GO:0001655ISS-urogenital system development-
GO:0007399TAS-nervous system development8589679
GO:0007411ISS-axon guidance-
GO:0007413ISS-axonal fasciculation-
GO:0016310ISS-phosphorylation-
GO:0018108ISS-peptidyl-tyrosine phosphorylation-
GO:0022038ISS-corpus callosum development-
GO:0042472ISS-inner ear morphogenesis-
GO:0048013ISS-ephrin receptor signaling pathway-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0050878ISS-regulation of body fluid levels-
GO:0051965ISS-positive regulation of synapse assembly-
GO:0060021ISS-palate development-
GO:0060996ISS-dendritic spine development-
GO:0060997ISS-dendritic spine morphogenesis-
GO:0071679ISS-commissural neuron axon guidance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPHB2ABL110836211494128 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EPHB2ABL110654311494128 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EPHB2ABL210654511494128 Two-hybrid
EPHB2ABL210836211494128 Two-hybrid
EPHB2ACP11065689499402 Affinity Capture-Western
EPHB2ACP11083629499402 Affinity Capture-Western
EPHB2ALK10673914968112 Affinity Capture-MS
EPHB2ALK10836214968112 Affinity Capture-MS
EPHB2BCL210836215225643 Biochemical Activity
EPHB2BCL210706815225643 Biochemical Activity
EPHB2CRK10836210644995 Reconstituted Complex
EPHB2CRK10778810644995 Reconstituted Complex
EPHB2EFNB210836211780069 Reconstituted Complex
EPHB2EFNB210826811780069 Reconstituted Complex
RASA1EPHB21083629233798 10644995 Affinity Capture-Western; Reconstituted Complex
RASA1EPHB21118569233798 10644995 Affinity Capture-Western; Reconstituted Complex
SRCEPHB21083629632142 10644995 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SRCEPHB21125929632142 10644995 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YES1EPHB21083629632142 Reconstituted Complex
YES1EPHB21133579632142 Reconstituted Complex
PLCG1EPHB21083629632142 Two-hybrid
PLCG1EPHB21113519632142 Two-hybrid
MLLT4EPHB21104479707552 Two-hybrid
MLLT4EPHB21083629707552 Two-hybrid
EPHB2EPHB21083629933164 Co-crystal Structure
MST4EPHB210836211641781 Phenotypic Enhancement
MST4EPHB211972211641781 Phenotypic Enhancement
RYKEPHB211217111956217 Affinity Capture-Western
RYKEPHB210836211956217 Affinity Capture-Western
ITSN1EPHB210836212389031 Affinity Capture-Western
ITSN1EPHB211235112389031 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
EPHB2rs10917325 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:99611
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070713-2'