AutismKB 2.0

Annotation Details for EPHB3


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Basic Information Top
Gene Symbol:EPHB3 ( ETK2,HEK2,TYRO6 )
Gene Full Name: EPH receptor B3
Band: 3q27.1
Quick LinksEntrez ID:2049; OMIM: 601839; Uniprot ID:EPHB3_HUMAN; ENSEMBL ID: ENSG00000182580; HGNC ID: 3394
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane8397371
GO:0030425IEA-dendrite-
GO ID Evidence Qualifier GO_term References
GO:0005003IDA-ephrin receptor activity8397371
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0001525ISS-angiogenesis-
GO:0001655ISS-urogenital system development-
GO:0007411ISS-axon guidance-
GO:0007413ISS-axonal fasciculation-
GO:0016477IDA-cell migration15536074
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0022038ISS-corpus callosum development-
GO:0022407IDA-regulation of cell-cell adhesion8397371
GO:0034446IDA-substrate adhesion-dependent cell spreading15536074
GO:0043087IDA-regulation of GTPase activity15536074
GO:0046777IDA-protein autophosphorylation8397371
GO:0048013IDA-ephrin receptor signaling pathway8397371
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0048538ISS-thymus development-
GO:0048546ISS-digestive tract morphogenesis-
GO:0050770ISS-regulation of axonogenesis-
GO:0051965ISS-positive regulation of synapse assembly-
GO:0060021ISS-palate development-
GO:0060996ISS-dendritic spine development-
GO:0060997ISS-dendritic spine morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPHB3CRK1083639674711 Reconstituted Complex
EPHB3CRK1077889674711 Reconstituted Complex
EPHB3EFNB31083639484836 Reconstituted Complex
EPHB3EFNB31082699484836 Reconstituted Complex
RASA1EPHB31083639674711 Affinity Capture-Western; Reconstituted Complex
RASA1EPHB31118569674711 Affinity Capture-Western; Reconstituted Complex
FYNEPHB31083639674711 Reconstituted Complex
FYNEPHB31088109674711 Reconstituted Complex
MLLT4EPHB31104479707552 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MLLT4EPHB31083639707552 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RYKEPHB311217111956217 Affinity Capture-Western
RYKEPHB310836311956217 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104770
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-100811-1'