AutismKB 2.0

Annotation Details for EPHX2


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Basic Information Top
Gene Symbol:EPHX2 ( CEH,SEH )
Gene Full Name: epoxide hydrolase 2, cytoplasmic
Band: 8p21.2-p21.1
Quick LinksEntrez ID:2053; OMIM: 132811; Uniprot ID:HYES_HUMAN; ENSEMBL ID: ENSG00000120915; HGNC ID: 3402
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005777IDA-peroxisome16314446
GO:0005829IDA-cytosol8342951
GO:0005829NAS-cytosol10862610
GO:0005829TAS-cytosol-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding12574510
GO:0004301IDA-epoxide hydrolase activity8342951
GO:0004301TAS-epoxide hydrolase activity-
GO:0005102IPI-receptor binding20178365
GO:0015643IDA-toxic substance binding15096040
GO:0016791IDA-phosphatase activity12574508
GO:0033885IEA-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity-
GO:0042577IDA-lipid phosphatase activity12574510
GO:0042803IDA-protein homodimerization activity15096040
GO:0042803NAS-protein homodimerization activity10862610
GO ID Evidence Qualifier GO_term References
GO:0006805NAS-xenobiotic metabolic process10862610
GO:0006874NAS-cellular calcium ion homeostasis10862610
GO:0006954NAS-inflammatory response10862610
GO:0008217NAS-regulation of blood pressure10862610
GO:0009636NAS-response to toxic substance10862610
GO:0010628IDA-positive regulation of gene expression18974052
GO:0016311IDA-dephosphorylation12574508
GO:0017144NAS-drug metabolic process10862610
GO:0019373TAS-epoxygenase P450 pathway-
GO:0042632IDA-cholesterol homeostasis18974052
GO:0046272IDA-stilbene catabolic process8342951
GO:0046839IDA-phospholipid dephosphorylation12574510
GO:0072593NAS-reactive oxygen species metabolic process10862610
GO:0090181IMP-regulation of cholesterol metabolic process18974052
GO:0097755NAS-positive regulation of blood vessel diameter10862610
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
EPHX2rs2234887, rs751141 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:99500
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041212-70'