AutismKB 2.0

Annotation Details for EPRS


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Basic Information Top
Gene Symbol:EPRS ( DKFZp313B047,EARS,GLUPRORS,PARS,QARS,QPRS )
Gene Full Name: glutamyl-prolyl-tRNA synthetase
Band: 1q41
Quick LinksEntrez ID:2058; OMIM: 138295; Uniprot ID:SYEP_HUMAN; ENSEMBL ID: ENSG00000136628; HGNC ID: 3418
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10791971
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0017101IBA-aminoacyl-tRNA synthetase multienzyme complex-
GO:0017101IDA-aminoacyl-tRNA synthetase multienzyme complex10791971
GO:0030529IDA-intracellular ribonucleoprotein complex15479637
GO:0097452IDA-GAIT complex15479637
GO ID Evidence Qualifier GO_term References
GO:0004818IBA-glutamate-tRNA ligase activity-
GO:0004818TAS-glutamate-tRNA ligase activity-
GO:0004827IBA-proline-tRNA ligase activity-
GO:0004827TAS-proline-tRNA ligase activity-
GO:0005515IPI-protein binding9556618
GO:0005524IEA-ATP binding-
GO:0035613IDA-RNA stem-loop binding15479637
GO:0051020IPI-GTPase binding24337748
GO ID Evidence Qualifier GO_term References
GO:0006418TAS-tRNA aminoacylation for protein translation-
GO:0006424IBA-glutamyl-tRNA aminoacylation-
GO:0006433IBA-prolyl-tRNA aminoacylation-
GO:0006461TAS-protein complex assembly8188258
GO:0017148IDA-negative regulation of translation23071094
GO:0017148IMP-negative regulation of translation15479637
GO:0071346IDA-cellular response to interferon-gamma15479637
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPRSARL4D10687416169070 Two-hybrid
EPRSARL4D10837216169070 Two-hybrid
POU2F1EPRS1114479537509 Far Western; Reconstituted Complex; Two-hybrid
POU2F1EPRS1083729537509 Far Western; Reconstituted Complex; Two-hybrid
IARSEPRS1083729556618 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IARSEPRS1096059556618 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RARSEPRS1083729556618 Two-hybrid
RARSEPRS1118529556618 Two-hybrid
HSP90AA1EPRS10837210913161 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
HSP90AA1EPRS10955210913161 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
NEDD4EPRS10837216055720 Affinity Capture-MS
NEDD4EPRS11081116055720 Affinity Capture-MS
TH1LEPRS11957216169070 Two-hybrid
TH1LEPRS10837216169070 Two-hybrid
MCCEPRS11033317353931 Affinity Capture-MS
MCCEPRS10837217353931 Affinity Capture-MS
TFE3EPRS11288817353931 Affinity Capture-MS
TFE3EPRS10837217353931 Affinity Capture-MS
IKBKEEPRS10837217353931 Affinity Capture-MS
IKBKEEPRS11500017353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97838
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-638'