AutismKB 2.0

Annotation Details for ERCC6


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Basic Information Top
Gene Symbol:ERCC6 ( ARMD5,CKN2,COFS,COFS1,CSB,RAD26 )
Gene Full Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Band: 10q11.23
Quick LinksEntrez ID:2074; OMIM: 609413; Uniprot ID:ERCC6_HUMAN; ENSEMBL ID: ENSG00000225830; HGNC ID: 3438
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12560492
GO:0005654IDA-nucleoplasm16107709
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus16107709
GO:0005794IDA-Golgi apparatus-
GO:0005829IDA-cytosol-
GO:0008023IDA-transcription elongation factor complex9326587
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding8999876
GO:0003678IDANOTDNA helicase activity8999876
GO:0003682IDA-chromatin binding16916636
GO:0005515IPI-protein binding7663514
GO:0005524IDA-ATP binding12560492
GO:0008022IPI-protein C-terminus binding16246722
GO:0008094IDA-DNA-dependent ATPase activity8999876
GO:0030296IDA-protein tyrosine kinase activator activity17626041
GO:0032403IDA-protein complex binding16916636
GO:0047485IPI-protein N-terminus binding7664335
GO ID Evidence Qualifier GO_term References
GO:0000303IEA-response to superoxide-
GO:0006283IMP-transcription-coupled nucleotide-excision repair10564257
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006284IMP-base-excision repair9973627
GO:0006290IEA-pyrimidine dimer repair-
GO:0006362IEA-transcription elongation from RNA polymerase I promoter-
GO:0006366NAS-transcription from RNA polymerase II promoter7664335
GO:0006979IDA-response to oxidative stress16107709
GO:0006979IGI-response to oxidative stress17626041
GO:0007256IEA-activation of JNKK activity-
GO:0007257IEA-activation of JUN kinase activity-
GO:0008630IEA-intrinsic apoptotic signaling pathway in response to DNA damage-
GO:0009411IDA-response to UV16916636
GO:0009636IEA-response to toxic substance-
GO:0010165IEA-response to X-ray-
GO:0010224IEA-response to UV-B-
GO:0010332IEA-response to gamma radiation-
GO:0032784IDA-regulation of DNA-templated transcription, elongation9326587
GO:0032786IDA-positive regulation of DNA-templated transcription, elongation9326587
GO:0035264IEA-multicellular organism growth-
GO:0045494IEA-photoreceptor cell maintenance-
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0061098IEA-positive regulation of protein tyrosine kinase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TP53ERCC61130107663514 10882116 Affinity Capture-Western; Reconstituted Complex
TP53ERCC61083867663514 10882116 Affinity Capture-Western; Reconstituted Complex
XPAERCC61133448999876 Reconstituted Complex
XPAERCC61083868999876 Reconstituted Complex
XAB2ERCC612127310944529 Affinity Capture-Western
XAB2ERCC610838610944529 Affinity Capture-Western
HIST1H2BBERCC610838611003660 Affinity Capture-Western; Far Western
HIST1H2BBERCC610927111003660 Affinity Capture-Western; Far Western
HIST1H2ABERCC610838611003660 Affinity Capture-Western; Far Western
HIST1H2ABERCC611393111003660 Affinity Capture-Western; Far Western
HIST1H3AERCC611394611003660 Affinity Capture-Western; Far Western
HIST1H3AERCC610838611003660 Affinity Capture-Western; Far Western
HIST1H4AERCC610838611003660 Affinity Capture-Western; Far Western
HIST1H4AERCC611395511003660 Affinity Capture-Western; Far Western
BAZ1BERCC611449716603771 Affinity Capture-MS; Affinity Capture-Western
BAZ1BERCC610838616603771 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1100494
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070228-1'