AutismKB 2.0

Annotation Details for ESRRB


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Basic Information Top
Gene Symbol:ESRRB ( DFNB35,ERR2,ERRb,ESRL2,NR3B2 )
Gene Full Name: estrogen-related receptor beta
Band: 14q24.3
Quick LinksEntrez ID:2103; OMIM: 602167; Uniprot ID:A2VDJ2_HUMAN; ENSEMBL ID: ENSG00000119715; HGNC ID: 3473
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000793ISS-condensed chromosome-
GO:0005634ISS-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005737ISS-cytoplasm-
GO:0032039ISScolocalizes_withintegrator complex-
GO ID Evidence Qualifier GO_term References
GO:0000980ISS-RNA polymerase II distal enhancer sequence-specific DNA binding-
GO:0000993ISS-RNA polymerase II core binding-
GO:0001047ISS-core promoter binding-
GO:0001158ISS-enhancer sequence-specific DNA binding-
GO:0001205ISS-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0003700ISS-transcription factor activity, sequence-specific DNA binding-
GO:0003705ISS-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0003707IEA-steroid hormone receptor activity-
GO:0003713ISS-transcription coactivator activity-
GO:0004879TAS-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding9344655
GO:0005496IEA-steroid binding-
GO:0008134ISS-transcription factor binding-
GO:0008270IEA-zinc ion binding-
GO:0035326ISS-enhancer binding-
GO:0043565IDA-sequence-specific DNA binding12654265
GO ID Evidence Qualifier GO_term References
GO:0001892NASNOTembryonic placenta development19196830
GO:0006355IDA-regulation of transcription, DNA-templated23836911
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0017145ISS-stem cell division-
GO:0019827IDA-stem cell population maintenance25522312
GO:0030522IEA-intracellular receptor signaling pathway-
GO:0043401IEA-steroid hormone mediated signaling pathway-
GO:0043697ISS-cell dedifferentiation-
GO:0045494ISS-photoreceptor cell maintenance-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0048839ISS-inner ear development-
GO:0071931ISS-positive regulation of transcription involved in G1/S transition of mitotic cell cycle-
GO:0090282ISS-positive regulation of transcription involved in G2/M transition of mitotic cell cycle-
GO:1902459ISS-positive regulation of stem cell population maintenance-
GO:2000035ISS-regulation of stem cell division-
GO:2000737ISS-negative regulation of stem cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCOA2ESRRB11576110598588 Reconstituted Complex
NCOA2ESRRB10840610598588 Reconstituted Complex
NCOA3ESRRB11384110598588 Reconstituted Complex
NCOA3ESRRB10840610598588 Reconstituted Complex
SP1ESRRB11255016439465 Reconstituted Complex
SP1ESRRB10840616439465 Reconstituted Complex
NRIP1ESRRB11384316439465 Reconstituted Complex
NRIP1ESRRB10840616439465 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1346832
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040616-2'