AutismKB 2.0

Annotation Details for ETS1


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Basic Information Top
Gene Symbol:ETS1 ( ETS-1,EWSR2,FLJ10768 )
Gene Full Name: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
Band: 11q24.3
Quick LinksEntrez ID:2113; OMIM: 164720; Uniprot ID:ETS1_HUMAN; ENSEMBL ID: ENSG00000134954; HGNC ID: 3488
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11909962
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding12119294
GO:0000982IDA-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding21711453
GO:0001077IC-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003677ISS-DNA binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding11909962
GO:0005515IPI-protein binding10698492
GO:0008134NAS-transcription factor binding10698492
GO:0035035IEA-histone acetyltransferase binding-
GO:0042802IPI-identical protein binding25609649
GO ID Evidence Qualifier GO_term References
GO:0001666IEA-response to hypoxia-
GO:0006955TAS-immune response2187191
GO:0007565IEA-female pregnancy-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008285TAS-negative regulation of cell proliferation2187191
GO:0009612IEA-response to mechanical stimulus-
GO:0010595IMP-positive regulation of endothelial cell migration15592518
GO:0010715IEA-regulation of extracellular matrix disassembly-
GO:0021854IEA-hypothalamus development-
GO:0021983IEA-pituitary gland development-
GO:0030578IDA-PML body organization11909962
GO:0032355IEA-response to estradiol-
GO:0034616IEA-response to laminar fluid shear stress-
GO:0044849IEA-estrous cycle-
GO:0045648IDA-positive regulation of erythrocyte differentiation8620536
GO:0045765IMP-regulation of angiogenesis15592518
GO:0045766IEA-positive regulation of angiogenesis-
GO:0045893IDA-positive regulation of transcription, DNA-templated11909962
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter15001984
GO:0048870IMP-cell motility15247905
GO:0050728IEA-negative regulation of inflammatory response-
GO:0050729IDA-positive regulation of inflammatory response21310411
GO:0051272IMP-positive regulation of cellular component movement15247905
GO:0060055IEA-angiogenesis involved in wound healing-
GO:0061614IDA-pri-miRNA transcription from RNA polymerase II promoter21711453
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0070555IEA-response to interleukin-1-
GO:1904996IMP-positive regulation of leukocyte adhesion to vascular endothelial cell21310411
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ETS1BRCA110714011313879 Reconstituted Complex
ETS1BRCA110841411313879 Reconstituted Complex
ETS1RUNX21073089794229 Reconstituted Complex
ETS1RUNX21084149794229 Reconstituted Complex
ETS1RUNX110730910207087 Reconstituted Complex
ETS1RUNX110841410207087 Reconstituted Complex
ETS1CREBBP1077779528793 15572696 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
ETS1CREBBP1084149528793 15572696 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
ETS1DAXX10798510698492 16861237 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ETS1DAXX10841410698492 16861237 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ETS1EP30010834710358095 10942770 15572696 Phenotypic Enhancement; Protein-peptide; Reconstituted Complex
ETS1EP30010841410358095 10942770 15572696 Phenotypic Enhancement; Protein-peptide; Reconstituted Complex
JUNETS11084148557686 Reconstituted Complex
JUNETS11099288557686 Reconstituted Complex
UBE2IETS11131779333025 Reconstituted Complex; Two-hybrid
UBE2IETS11084149333025 Reconstituted Complex; Two-hybrid
ETS2ETS11084149334186 Reconstituted Complex
ETS2ETS11084159334186 Reconstituted Complex
MAFETS11084149566892 Reconstituted Complex
MAFETS11102699566892 Reconstituted Complex
SPI1ETS11084149681824 Reconstituted Complex
SPI1ETS11125669681824 Reconstituted Complex
TDP2ETS110841412743594 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TDP2ETS111961512743594 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MED23ETS111482915572696 Protein-peptide
MED23ETS110841415572696 Protein-peptide
SRCETS111259215788656 Affinity Capture-Western
SRCETS110841415788656 Affinity Capture-Western
NCOA3ETS111384115788656 Affinity Capture-Western
NCOA3ETS110841415788656 Affinity Capture-Western
NCOR1ETS111497315788656 Affinity Capture-Western
NCOR1ETS110841415788656 Affinity Capture-Western
PIAS4ETS111962417456046 Affinity Capture-Western
PIAS4ETS110841417456046 Affinity Capture-Western
UBCETS111316417456046 Reconstituted Complex
UBCETS110841417456046 Reconstituted Complex
RBBP6ETS110841418851979 Two-hybrid
RBBP6ETS111186518851979 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95455
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021115-5'