AutismKB 2.0

Annotation Details for ALAS2


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Basic Information Top
Gene Symbol:ALAS2 ( ALAS-E,ALASE,ANH1,ASB,FLJ93603,XLDPP,XLSA )
Gene Full Name: aminolevulinate, delta-, synthase 2
Band: Xp11.21
Quick LinksEntrez ID:212; OMIM: 301300; Uniprot ID:HEM0_HUMAN; ENSEMBL ID: ENSG00000158578; HGNC ID: 397
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion10727444
GO:0005743IDA-mitochondrial inner membrane14643893
GO:0005759TAS-mitochondrial matrix-
GO ID Evidence Qualifier GO_term References
GO:0003870IDA-5-aminolevulinate synthase activity14643893
GO:0003870TAS-5-aminolevulinate synthase activity-
GO:0005515IPI-protein binding10727444
GO:0016594ISS-glycine binding-
GO:0030170IEA-pyridoxal phosphate binding-
GO:0050662ISS-coenzyme binding-
GO ID Evidence Qualifier GO_term References
GO:0001666IDA-response to hypoxia16234850
GO:0006782IEA-protoporphyrinogen IX biosynthetic process-
GO:0006783ISS-heme biosynthetic process-
GO:0006783NAS-heme biosynthetic process14643893
GO:0006783TAS-heme biosynthetic process-
GO:0006879ISS-cellular iron ion homeostasis-
GO:0030218ISS-erythrocyte differentiation-
GO:0030218NAS-erythrocyte differentiation2050125
GO:0032364NAS-oxygen homeostasis16234850
GO:0042541ISS-hemoglobin biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SUCLA2ALAS211433110727444 Affinity Capture-Western
SUCLA2ALAS210671410727444 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:87990
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001229-1'