AutismKB 2.0

Annotation Details for FBLN1


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Basic Information Top
Gene Symbol:FBLN1 ( FBLN,FIBL1 )
Gene Full Name: fibulin 1
Band: 22q13.31
Quick LinksEntrez ID:2192; OMIM: 135820; Uniprot ID:FBLN1_HUMAN; ENSEMBL ID: ENSG00000077942; HGNC ID: 3600
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005577IDAcolocalizes_withfibrinogen complex7642629
GO:0005578IDA-proteinaceous extracellular matrix2269669
GO:0005604IEA-basement membrane-
GO:0005615IDA-extracellular space2269669
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0070062IDA-extracellular exosome23376485
GO:0071953IDA-elastic fiber7534784
GO ID Evidence Qualifier GO_term References
GO:0001968IPI-fibronectin binding1400330
GO:0005201IDA-extracellular matrix structural constituent2269669
GO:0005509IDA-calcium ion binding9278415
GO:0008022IPI-protein C-terminus binding11238726
GO:0016504IEA-peptidase activator activity-
GO:0032403IPI-protein complex binding7642629
GO:0042802IDA-identical protein binding1400330
GO:0070051IPI-fibrinogen binding7642629
GO ID Evidence Qualifier GO_term References
GO:0001933IDA-negative regulation of protein phosphorylation11792823
GO:0007162IDA-negative regulation of cell adhesion11792823
GO:0007229IDANOTintegrin-mediated signaling pathway11792823
GO:0007566IEA-embryo implantation-
GO:0010952IEA-positive regulation of peptidase activity-
GO:0016032IEA-viral process-
GO:0030198IEA-extracellular matrix organization-
GO:0070373IDA-negative regulation of ERK1 and ERK2 cascade11792823
GO:0072378IDA-blood coagulation, fibrin clot formation7642629
GO:1900025IDA-negative regulation of substrate adhesion-dependent cell spreading11792823
GO:2000146IDA-negative regulation of cell motility11792823
GO:2000647IDA-negative regulation of stem cell proliferation11238726
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FBLN1APP10684811238726 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FBLN1APP10848611238726 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FBLN1CTGF1078729927660 Reconstituted Complex
FBLN1CTGF1084869927660 Reconstituted Complex
FBLN1ELN10848610544250 Reconstituted Complex
FBLN1ELN10832110544250 Reconstituted Complex
FN1FBLN11086211400330 Reconstituted Complex
FN1FBLN11084861400330 Reconstituted Complex
FGBFBLN11085357642629 Reconstituted Complex
FGBFBLN11084867642629 Reconstituted Complex
NID1FBLN11084868354280 9278415 9299350 Reconstituted Complex
NID1FBLN11108768354280 9278415 9299350 Reconstituted Complex
FBLN1FBLN11084869278415 Reconstituted Complex
NOVFBLN11109189927660 Reconstituted Complex; Two-hybrid
NOVFBLN11084869927660 Reconstituted Complex; Two-hybrid
MPGFBLN110848617353931 Affinity Capture-MS
MPGFBLN111049017353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95487
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-73'