AutismKB 2.0

Annotation Details for FASN


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Basic Information Top
Gene Symbol:FASN ( FAS,MGC14367,MGC15706,OA-519,SDR27X1 )
Gene Full Name: fatty acid synthase
Band: 17q25.3
Quick LinksEntrez ID:2194; OMIM: 600212; Uniprot ID:FAS_HUMAN; ENSEMBL ID: ENSG00000169710; HGNC ID: 3594
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IEA-mitochondrion-
GO:0005794IDA-Golgi apparatus-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0016020IDA-membrane16210410
GO:0042470IEA-melanosome-
GO:0042587IEA-glycogen granule-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0004312TAS-fatty acid synthase activity-
GO:0004313IEA-[acyl-carrier-protein] S-acetyltransferase activity-
GO:0004314IEA-[acyl-carrier-protein] S-malonyltransferase activity-
GO:0004315IEA-3-oxoacyl-[acyl-carrier-protein] synthase activity-
GO:0004316IEA-3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity-
GO:0004317IEA-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity-
GO:0004319IEA-enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity-
GO:0004320IEA-oleoyl-[acyl-carrier-protein] hydrolase activity-
GO:0005515IPI-protein binding18022563
GO:0008144IEA-drug binding-
GO:0016295IEA-myristoyl-[acyl-carrier-protein] hydrolase activity-
GO:0016296IEA-palmitoyl-[acyl-carrier-protein] hydrolase activity-
GO:0031177IEA-phosphopantetheine binding-
GO:0042803IEA-protein homodimerization activity-
GO:0045296IDA-cadherin binding25468996
GO:0047117IEA-enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity-
GO:0047451IEA-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity-
GO:0070402IEA-NADPH binding-
GO:0102131IEA-3-oxo-glutaryl-[acp] methyl ester reductase activity-
GO:0102132IEA-3-oxo-pimeloyl-[acp] methyl ester reductase activity-
GO ID Evidence Qualifier GO_term References
GO:0001649IDA-osteoblast differentiation16210410
GO:0006084IEA-acetyl-CoA metabolic process-
GO:0006631TAS-fatty acid metabolic process7835891
GO:0006633IEA-fatty acid biosynthetic process-
GO:0015939TAS-pantothenate metabolic process-
GO:0030879IEA-mammary gland development-
GO:0031325TAS-positive regulation of cellular metabolic process-
GO:0045540TAS-regulation of cholesterol biosynthetic process-
GO:0046949TAS-fatty-acyl-CoA biosynthetic process-
GO:0055114IEA-oxidation-reduction process-
GO:0071353IEA-cellular response to interleukin-4-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FASNEWSR110843116189514 Two-hybrid
FASNEWSR110848816189514 Two-hybrid
FASNFASN10848811248039 Two-hybrid
USP2FASN11455315050917 Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
USP2FASN10848815050917 Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
UBCFASN11316415050917 Affinity Capture-Western
UBCFASN10848815050917 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95485
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7802'