AutismKB 2.0

Annotation Details for FGD1


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Basic Information Top
Gene Symbol:FGD1 ( AAS,FGDY,MRXS16,ZFYVE3 )
Gene Full Name: FYVE, RhoGEF and PH domain containing 1
Band: Xp11.22
Quick LinksEntrez ID:2245; OMIM: 300546; Uniprot ID:FGD1_HUMAN; ENSEMBL ID: ENSG00000102302; HGNC ID: 3663
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726ISS-ruffle-
GO:0005737ISS-cytoplasm-
GO:0005794ISS-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0030027ISS-lamellipodium-
GO ID Evidence Qualifier GO_term References
GO:0005085IDA-guanyl-nucleotide exchange factor activity8969170
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO:0031267IDA-small GTPase binding8969170
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007010ISS-cytoskeleton organization-
GO:0007165TAS-signal transduction8969170
GO:0007275TAS-multicellular organism development8969170
GO:0008360ISS-regulation of cell shape-
GO:0009887TAS-animal organ morphogenesis7954831
GO:0030036IDA-actin cytoskeleton organization8969170
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043087IDA-regulation of GTPase activity8969170
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046847IDA-filopodium assembly8969170
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FGD1CDC421074338969170 Reconstituted Complex
FGD1CDC421085368969170 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104566
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081104-33'