AutismKB 2.0

Annotation Details for FGF12


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Basic Information Top
Gene Symbol:FGF12 ( FGF12B,FHF1 )
Gene Full Name: fibroblast growth factor 12
Band: 3q28-q29
Quick LinksEntrez ID:2257; OMIM: 601513; Uniprot ID:FGF12_HUMAN; ENSEMBL ID: ENSG00000114279; HGNC ID: 3668
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615TAS-extracellular space10049777
GO:0005634IDA-nucleus8790420
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0008083IEA-growth factor activity-
GO:0017080ISS-sodium channel regulator activity12401812
GO:0044325ISS-ion channel binding12401812
GO ID Evidence Qualifier GO_term References
GO:0003254IEA-regulation of membrane depolarization-
GO:0007165TAS-signal transduction8790420
GO:0007267TAS-cell-cell signaling8790420
GO:0007268IEA-chemical synaptic transmission-
GO:0007399TAS-nervous system development8790420
GO:0007507TAS-heart development10049777
GO:0008344IEA-adult locomotory behavior-
GO:0008543IEA-fibroblast growth factor receptor signaling pathway-
GO:0010765IEA-positive regulation of sodium ion transport-
GO:0050905IEA-neuromuscular process-
GO:0086002NAS-cardiac muscle cell action potential involved in contraction12401812
GO:0098908IMP-regulation of neuronal action potential27164707
GO:1902305ISS-regulation of sodium ion transmembrane transport12401812
GO:1905150IMP-regulation of voltage-gated sodium channel activity27164707
GO:2000649ISS-regulation of sodium ion transmembrane transporter activity12401812
GO:2001258IEA-negative regulation of cation channel activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAPK8IP2FGF1210854811378392 Affinity Capture-Western
MAPK8IP2FGF1211708611378392 Affinity Capture-Western
MAPK13FGF1210854812244047 Biochemical Activity
MAPK13FGF1211158912244047 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109183
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050221-6'