AutismKB 2.0

Annotation Details for MTF2


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Basic Information Top
Gene Symbol:MTF2 ( M96,PCL2,RP5-976O13.1,dJ976O13.2 )
Gene Full Name: metal response element binding transcription factor 2
Band: 1p22.1
Quick LinksEntrez ID:22823; OMIM: 609882; Uniprot ID:MTF2_HUMAN; ENSEMBL ID: ENSG00000143033; HGNC ID: 29535
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus8619255
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm8619255
GO:0035098ISScolocalizes_withESC/E(Z) complex-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0035064IDA-methylated histone binding23142980
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122ISS-negative regulation of transcription from RNA polymerase II promoter-
GO:0007379ISS-segment specification-
GO:0016569IEA-covalent chromatin modification-
GO:0019827ISS-stem cell population maintenance-
GO:0045814TAS-negative regulation of gene expression, epigenetic-
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0048863ISS-stem cell differentiation-
GO:0061086ISS-negative regulation of histone H3-K27 methylation-
GO:0061087ISS-positive regulation of histone H3-K27 methylation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MTF2CREB111649920211142 Two-hybrid
MTF2CREB110777520211142 Two-hybrid
MTF2EZH210844620123894 Affinity Capture-MS; Affinity Capture-Western
MTF2EZH211649920123894 Affinity Capture-MS; Affinity Capture-Western
MTF2JARID210992320123894 Affinity Capture-Western
MTF2JARID211649920123894 Affinity Capture-Western
SUZ12MTF211705920123894 Affinity Capture-Western
SUZ12MTF211649920123894 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105050
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060512-94'