AutismKB 2.0

Annotation Details for INPP5F


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Basic Information Top
Gene Symbol:INPP5F ( FLJ13081,KIAA0966,MGC131851,MGC59773,MSTPO47,SAC2,hSAC2 )
Gene Full Name: inositol polyphosphate-5-phosphatase F
Band: 10q26.11
Quick LinksEntrez ID:22876; OMIM: 609389; Uniprot ID:SAC2_HUMAN; ENSEMBL ID: ENSG00000198825; HGNC ID: 17054
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005769IDA-early endosome25869669
GO:0005905IDAcolocalizes_withclathrin-coated pit25869669
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0031901TAS-early endosome membrane-
GO:0043025IEA-neuronal cell body-
GO:0045334IDA-clathrin-coated endocytic vesicle25869669
GO:0055037IDA-recycling endosome25869669
GO:0055037ISS-recycling endosome-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25476455
GO:0008934IEA-inositol monophosphate 1-phosphatase activity-
GO:0034595IDA-phosphatidylinositol phosphate 5-phosphatase activity11274189
GO:0034595IDANOTphosphatidylinositol phosphate 5-phosphatase activity25869669
GO:0034596IDA-phosphatidylinositol phosphate 4-phosphatase activity25869669
GO:0034596TAS-phosphatidylinositol phosphate 4-phosphatase activity-
GO:0042803IDA-protein homodimerization activity25869669
GO:0042803ISS-protein homodimerization activity-
GO:0052832IEA-inositol monophosphate 3-phosphatase activity-
GO:0052833IEA-inositol monophosphate 4-phosphatase activity-
GO ID Evidence Qualifier GO_term References
GO:0001921IDA-positive regulation of receptor recycling25869669
GO:0006661TAS-phosphatidylinositol biosynthetic process-
GO:0008344IEA-adult locomotory behavior-
GO:0014898ISS-cardiac muscle hypertrophy in response to stress-
GO:0031161ISS-phosphatidylinositol catabolic process-
GO:0033137IEA-negative regulation of peptidyl-serine phosphorylation-
GO:0042532IDA-negative regulation of tyrosine phosphorylation of STAT protein25476455
GO:0046856IDA-phosphatidylinositol dephosphorylation11274189
GO:0048015ISS-phosphatidylinositol-mediated signaling-
GO:0048681ISS-negative regulation of axon regeneration-
GO:0051896IEA-regulation of protein kinase B signaling-
GO:0072583ISS-clathrin-dependent endocytosis-
GO:2000145IMP-regulation of cell motility25869669
GO:2001135IMP-regulation of endocytic recycling25869669
GO:2001135ISS-regulation of endocytic recycling-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2141867
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041111-194'