AutismKB 2.0

Annotation Details for ZHX2


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Basic Information Top
Gene Symbol:ZHX2 ( AFR1,KIAA0854,RAF )
Gene Full Name: zinc fingers and homeoboxes 2
Band: 8q24.13
Quick LinksEntrez ID:22882; OMIM: 609185; Uniprot ID:ZHX2_HUMAN; ENSEMBL ID: ENSG00000178764; HGNC ID: 18513
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12741956
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding12741956
GO:0003714IDA-transcription corepressor activity12741956
GO:0005515IPI-protein binding12741956
GO:0042802IPI-identical protein binding12741956
GO:0042803IDA-protein homodimerization activity12741956
GO:0046872IEA-metal ion binding-
GO:0046982IDA-protein heterodimerization activity12741956
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter12741956
GO:0006351IEA-transcription, DNA-templated-
GO:0006402IEA-mRNA catabolic process-
GO:0035019IEA-somatic stem cell population maintenance-
GO:0045665IEA-negative regulation of neuron differentiation-
GO:0045892IDA-negative regulation of transcription, DNA-templated12741956
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZHX2HRAS10950117533377 Two-hybrid
ZHX2HRAS11654917533377 Two-hybrid
ZHX2IDE1165498051160 Co-purification
ZHX2IDE1096428051160 Co-purification
ZHX2RRAS11215119805522 Affinity Capture-Western
ZHX2RRAS11654919805522 Affinity Capture-Western
ZHX3ZHX211668814659886 Reconstituted Complex; Two-hybrid
ZHX3ZHX211654914659886 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2683087
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031107-2'