AutismKB 2.0

Annotation Details for DIS3


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Basic Information Top
Gene Symbol:DIS3 ( DKFZp667L1817,EXOSC11,FLJ10484,KIAA1008,MGC33035,RP11-342J4.3,RRP44,bA555G22.1,dis3p )
Gene Full Name: DIS3 mitotic control homolog (S. cerevisiae)
Band: 13q21.33
Quick LinksEntrez ID:22894; OMIM: 607533; Uniprot ID:RRP44_HUMAN; ENSEMBL ID: ENSG00000083520; HGNC ID: 20604
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000176IDA-nuclear exosome (RNase complex)20531386
GO:0000178TAS-exosome (RNase complex)9562621
GO:0005634IDA-nucleus-
GO:0005654IDA-nucleoplasm20531389
GO:0005730IDANOTnucleolus20531386
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0000175IMP-3'-5'-exoribonuclease activity20531386
GO:0000175TAS-3'-5'-exoribonuclease activity-
GO:0003723IEA-RNA binding-
GO:0004519IMP-endonuclease activity20531386
GO:0005085IDA-guanyl-nucleotide exchange factor activity9562621
GO:0005515IPI-protein binding15231747
GO ID Evidence Qualifier GO_term References
GO:0006364TAS-rRNA processing9562621
GO:0016075IMP-rRNA catabolic process20368444
GO:0043488TAS-regulation of mRNA stability-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0043928TAS-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-
GO:0071034IMP-CUT catabolic process19056938
GO:0090503IEA-RNA phosphodiester bond hydrolysis, exonucleolytic-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DIS3ZBTB1711350315231747 Two-hybrid
DIS3ZBTB1711655915231747 Two-hybrid
C19orf62DIS311885519615732 Affinity Capture-MS
C19orf62DIS311655919615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919912
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080213-3'