AutismKB 2.0

Annotation Details for TPX2


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Basic Information Top
Gene Symbol:TPX2 ( C20orf1,C20orf2,DIL-2,DIL2,FLS353,GD:C20orf1,HCA519,HCTP4,REPP86,p100 )
Gene Full Name: TPX2, microtubule-associated, homolog (Xenopus laevis)
Band: 20q11.21
Quick LinksEntrez ID:22974; OMIM: 605917; Uniprot ID:TPX2_HUMAN; ENSEMBL ID: ENSG00000088325; HGNC ID: 1249
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000922IDAcolocalizes_withspindle pole14718566
GO:0005634TAS-nucleus9207457
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005819ISS-spindle18663142
GO:0005829TAS-cytosol-
GO:0005874IEA-microtubule-
GO:0015630IDA-microtubule cytoskeleton-
GO:0043203IEA-axon hillock-
GO:0072686IDA-mitotic spindle-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding14580337
GO:0005524TAS-ATP binding10512675
GO:0005525TAS-GTP binding10512675
GO:0019901IPI-protein kinase binding14580337
GO:0061676IDA-importin-alpha family protein binding26165940
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0000278TAS-mitotic cell cycle9207457
GO:0006915IEA-apoptotic process-
GO:0008283TAS-cell proliferation10512675
GO:0032147IDA-activation of protein kinase activity14580337
GO:0051301IEA-cell division-
GO:0060236ISS-regulation of mitotic spindle organization18663142
GO:0090307IDA-mitotic spindle assembly26165940
GO:1901796TAS-regulation of signal transduction by p53 class mediator-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TPX2KPNA111003414600264 Affinity Capture-Western
TPX2KPNA111662414600264 Affinity Capture-Western
TPX2KPNB111003514600264 Affinity Capture-Western
TPX2KPNB111662414600264 Affinity Capture-Western
TPX2AURKA11266612177045 14600264 18773538 Affinity Capture-Western; Reconstituted Complex
TPX2AURKA11662412177045 14600264 18773538 Affinity Capture-Western; Reconstituted Complex
FZR1TPX211948916287863 Affinity Capture-Western
FZR1TPX211662416287863 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919369
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9652'