AutismKB 2.0

Annotation Details for RIMS1


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Basic Information Top
Gene Symbol:RIMS1 ( CORD7,KIAA0340,MGC167823,MGC176677,RAB3IP2,RIM,RIM1 )
Gene Full Name: regulating synaptic membrane exocytosis 1
Band: 6q13
Quick LinksEntrez ID:22999; OMIM: 606629; Uniprot ID:RIMS1_HUMAN; ENSEMBL ID: ENSG00000079841; HGNC ID: 17282
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886ISS-plasma membrane-
GO:0030054IEA-cell junction-
GO:0042734ISS-presynaptic membrane-
GO:0042734NAS-presynaptic membrane11438518
GO:0048786TAS-presynaptic active zone15217342
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding11438518
GO:0017137ISS-Rab GTPase binding-
GO:0030695TAS-GTPase regulator activity11438518
GO:0044325IBA-ion channel binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006461IDA-protein complex assembly11438518
GO:0006886IEA-intracellular protein transport-
GO:0007269TAS-neurotransmitter secretion-
GO:0007601IEA-visual perception-
GO:0010628ISS-positive regulation of gene expression-
GO:0014047TAS-glutamate secretion-
GO:0016079TAS-synaptic vesicle exocytosis11438518
GO:0017156TAS-calcium ion regulated exocytosis11438518
GO:0042391IBA-regulation of membrane potential-
GO:0045055NAS-regulated exocytosis11438518
GO:0046903NAS-secretion11438518
GO:0046928TAS-regulation of neurotransmitter secretion15217342
GO:0048791IBA-calcium ion-regulated exocytosis of neurotransmitter-
GO:0050790IEA-regulation of catalytic activity-
GO:0050896IEA-response to stimulus-
GO:0061025NAS-membrane fusion11438518
GO:0097151ISS-positive regulation of inhibitory postsynaptic potential-
GO:1903861IDA-positive regulation of dendrite extension23999003
GO:2000300IBA-regulation of synaptic vesicle exocytosis-
GO:2000463ISS-positive regulation of excitatory postsynaptic potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RIMS1CAMK2A11664612871946 Biochemical Activity
RIMS1CAMK2A10726512871946 Biochemical Activity
RIMS1RAB3A11664611343654 12578829 Affinity Capture-Western; Reconstituted Complex
RIMS1RAB3A11180211343654 12578829 Affinity Capture-Western; Reconstituted Complex
RIMS1RAB3B11664612578829 Affinity Capture-Western
RIMS1RAB3B11180312578829 Affinity Capture-Western
RIMS1YWHAH11664612871946 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RIMS1YWHAH11336512871946 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RIMS1BSN11664614734538 Affinity Capture-Western
RIMS1BSN11444114734538 Affinity Capture-Western
RIMS1RAB3D11664612578829 Affinity Capture-Western
RIMS1RAB3D11491912578829 Affinity Capture-Western
RIMS1UNC13B11575911343654 12163476 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RIMS1UNC13B11664611343654 12163476 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RIMS1RAB1011609612578829 Affinity Capture-Western
RIMS1RAB1011664612578829 Affinity Capture-Western
ERC2RIMS111664612163476 14734538 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
ERC2RIMS111752112163476 14734538 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
RAB3CRIMS111664612578829 Affinity Capture-Western
RAB3CRIMS112545912578829 Affinity Capture-Western
RAB26RIMS111664612578829 Affinity Capture-Western
RAB26RIMS111736412578829 Affinity Capture-Western
RAB37RIMS113060412578829 Affinity Capture-Western
RAB37RIMS111664612578829 Affinity Capture-Western
LRRK1RIMS112282317353931 Affinity Capture-MS
LRRK1RIMS111664617353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data