AutismKB 2.0

Annotation Details for FAIM2


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Basic Information Top
Gene Symbol:FAIM2 ( KIAA0950,LFG,LFG2,NGP35,NMP35,TMBIM2 )
Gene Full Name: Fas apoptotic inhibitory molecule 2
Band: 12q13.12
Quick LinksEntrez ID:23017; OMIM: 604306; Uniprot ID:FAIM2_HUMAN; ENSEMBL ID: ENSG00000135472; HGNC ID: 17067
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005783IEA-endoplasmic reticulum-
GO:0005794IEA-Golgi apparatus-
GO:0016021IEA-integral component of membrane-
GO:0030054IEA-cell junction-
GO:0045121IDA-membrane raft17635665
GO:0045211IEA-postsynaptic membrane-
No data
GO ID Evidence Qualifier GO_term References
GO:0002931IEA-response to ischemia-
GO:0006915IEA-apoptotic process-
GO:0021549ISS-cerebellum development-
GO:0021680ISS-cerebellar Purkinje cell layer development-
GO:0021681ISS-cerebellar granular layer development-
GO:0021702ISS-cerebellar Purkinje cell differentiation-
GO:0043066NAS-negative regulation of apoptotic process10535980
GO:0043523IMP-regulation of neuron apoptotic process17635665
GO:0043524IEA-negative regulation of neuron apoptotic process-
GO:1902042IDA-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors26582200
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FAIM2FAS10685110535980 Affinity Capture-Western
FAIM2FAS11665910535980 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919643
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018