AutismKB 2.0

Annotation Details for TNIK


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Basic Information Top
Gene Symbol:TNIK ( - )
Gene Full Name: TRAF2 and NCK interacting kinase
Band: 3q26.2-q26.31
Quick LinksEntrez ID:23043; OMIM: 610005; Uniprot ID:TNIK_HUMAN; ENSEMBL ID: ENSG00000154310; HGNC ID: 30765
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus19816403
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm15342639
GO:0005829IDA-cytosol-
GO:0005856IDA-cytoskeleton15342639
GO:0016324IDA-apical plasma membrane22797597
GO:0055037IEA-recycling endosome-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0004672IDA-protein kinase activity22797597
GO:0004674IDA-protein serine/threonine kinase activity10521462
GO:0004702IBA-signal transducer, downstream of receptor, with serine/threonine kinase activity-
GO:0005515IPI-protein binding10521462
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0001934IMP-positive regulation of protein phosphorylation22797597
GO:0006468IDA-protein phosphorylation10521462
GO:0007010IMP-cytoskeleton organization10521462
GO:0007256IDA-activation of JNKK activity15342639
GO:0007256IMP-activation of JNKK activity10521462
GO:0016055IEA-Wnt signaling pathway-
GO:0030033IMP-microvillus assembly22797597
GO:0031532IDA-actin cytoskeleton reorganization15342639
GO:0035556IDA-intracellular signal transduction10521462
GO:0046777IDA-protein autophosphorylation10521462
GO:0048814IDA-regulation of dendrite morphogenesis20159449
GO:0072659IMP-protein localization to plasma membrane22797597
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNIKSLC9A111243811369779 Reconstituted Complex
TNIKSLC9A111668211369779 Reconstituted Complex
TNIKTRAF211303810521462 Affinity Capture-Western
TNIKTRAF211668210521462 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1916264
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3767'