AutismKB 2.0

Annotation Details for FOXM1


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Basic Information Top
Gene Symbol:FOXM1 ( FKHL16,FOXM1B,HFH-11,HFH11,HNF-3,INS-1,MPHOSPH2,MPP-2,MPP2,PIG29,TGT3,TRIDENT )
Gene Full Name: forkhead box M1
Band: 12p13.33
Quick LinksEntrez ID:2305; OMIM: 602341; Uniprot ID:FOXM1_HUMAN; ENSEMBL ID: ENSG00000111206; HGNC ID: 3818
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654TAS-nucleoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000981IBA-RNA polymerase II transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding16504183
GO:0019901IPI-protein kinase binding19160488
GO:0043565IEA-sequence-specific DNA binding-
GO ID Evidence Qualifier GO_term References
GO:0000086IDA-G2/M transition of mitotic cell cycle19160488
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter20531406
GO:0006281IEA-DNA repair-
GO:0006351IEA-transcription, DNA-templated-
GO:0006978IMP-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator17101782
GO:0008284IMP-positive regulation of cell proliferation19696738
GO:0032873IMP-negative regulation of stress-activated MAPK cascade19696738
GO:0045892IMP-negative regulation of transcription, DNA-templated20531406
GO:0045893IMP-positive regulation of transcription, DNA-templated17101782
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter19160488
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter20531406
GO:0046578IMP-regulation of Ras protein signal transduction19696738
GO:0051726TAS-regulation of cell cycle-
GO:0071156IMP-regulation of cell cycle arrest19696738
GO:0090344IMP-negative regulation of cell aging19696738
GO:2000377IMP-regulation of reactive oxygen species metabolic process19696738
GO:2000781IMP-positive regulation of double-strand break repair17101782
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FOXM1CCNB110733215024056 Affinity Capture-Western
FOXM1CCNB110859415024056 Affinity Capture-Western
FOXM1CCNE110733815024056 Affinity Capture-Western
FOXM1CCNE110859415024056 Affinity Capture-Western
FOXM1CDK110742015024056 Affinity Capture-Western; Biochemical Activity
FOXM1CDK110859415024056 Affinity Capture-Western; Biochemical Activity
FOXM1CDC25B10742915024056 Affinity Capture-Western
FOXM1CDC25B10859415024056 Affinity Capture-Western
FOXM1CDH110743418758239 Affinity Capture-Western
FOXM1CDH110859418758239 Affinity Capture-Western
FOXM1CDK210745215024056 Affinity Capture-Western
FOXM1CDK210859415024056 Affinity Capture-Western
FOXM1CREBBP10777715024056 Affinity Capture-Western
FOXM1CREBBP10859415024056 Affinity Capture-Western
RB1FOXM111186015024056 Affinity Capture-Western
RB1FOXM110859415024056 Affinity Capture-Western
CHEK2FOXM111636917101782 Biochemical Activity
CHEK2FOXM110859417101782 Biochemical Activity
ZBTB3FOXM112293320211142 Two-hybrid
ZBTB3FOXM110859420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1347487
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1275'