AutismKB 2.0

Annotation Details for NCOA6


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Basic Information Top
Gene Symbol:NCOA6 ( AIB3,ASC2,KIAA0181,NRC,PRIP,RAP250,TRBP )
Gene Full Name: nuclear receptor coactivator 6
Band: 20q11.22
Quick LinksEntrez ID:23054; OMIM: 605299; Uniprot ID:NCOA6_HUMAN; ENSEMBL ID: ENSG00000198646; HGNC ID: 15936
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11443112
GO:0005634NAS-nucleus10567404
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667TAS-transcription factor complex11443112
GO:0005829IDA-cytosol-
GO:0035097IDA-histone methyltransferase complex17500065
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003682ISS-chromatin binding-
GO:0003713IDA-transcription coactivator activity10567404
GO:0005515IPI-protein binding10866662
GO:0019899IPI-enzyme binding12039952
GO:0030331TAS-estrogen receptor binding11443112
GO:0030374IPI-ligand-dependent nuclear receptor transcription coactivator activity11443112
GO:0046965TAS-retinoid X receptor binding11443112
GO:0046966IDA-thyroid hormone receptor binding11443112
GO ID Evidence Qualifier GO_term References
GO:0006260NAS-DNA replication11443112
GO:0006281NAS-DNA repair11443112
GO:0006310NAS-DNA recombination11443112
GO:0006352IDA-DNA-templated transcription, initiation10567404
GO:0006367ISS-transcription initiation from RNA polymerase II promoter-
GO:0006974IDA-cellular response to DNA damage stimulus17500065
GO:0007420ISS-brain development-
GO:0007507ISS-heart development-
GO:0009725TAS-response to hormone11443112
GO:0019216TAS-regulation of lipid metabolic process-
GO:0030099IDA-myeloid cell differentiation11302752
GO:0030520NAS-intracellular estrogen receptor signaling pathway11443112
GO:0042921NAS-glucocorticoid receptor signaling pathway11443112
GO:0045893TAS-positive regulation of transcription, DNA-templated12519782
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter11443112
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCOA6PARP110665212519782 Affinity Capture-MS
NCOA6PARP111669112519782 Affinity Capture-MS
NCOA6AR11669114645241 Affinity Capture-Western; Two-hybrid
NCOA6AR10686214645241 Affinity Capture-Western; Two-hybrid
NCOA6ASCL211669112482968 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NCOA6ASCL210692212482968 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NCOA6BCL310707410497212 Reconstituted Complex
NCOA6BCL311669110497212 Reconstituted Complex
NCOA6CD4011669110847592 Reconstituted Complex
NCOA6CD4010739610847592 Reconstituted Complex
NCOA6CEBPA11669111302752 Affinity Capture-Western
NCOA6CEBPA10747911302752 Affinity Capture-Western
NCOA6ATF211669114734562 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6ATF210777614734562 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6CREBBP11669110567404 11158331 Reconstituted Complex; Two-hybrid
NCOA6CREBBP10777710567404 11158331 Reconstituted Complex; Two-hybrid
NCOA6E2F110820114638867 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6E2F111669114638867 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6EP30010834710823961 Affinity Capture-Western; Reconstituted Complex
NCOA6EP30011669110823961 Affinity Capture-Western; Reconstituted Complex
NCOA6ESR110840310567404 11773444 16794079 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6ESR111669110567404 11773444 16794079 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6ESR211669111158331 11773444 Reconstituted Complex; Two-hybrid
NCOA6ESR210840411158331 11773444 Reconstituted Complex; Two-hybrid
NCOA6FGR11669112482968 Affinity Capture-Western
NCOA6FGR10855912482968 Affinity Capture-Western
NCOA6FOS11669110847592 Reconstituted Complex
NCOA6FOS10863610847592 Reconstituted Complex
NCOA6XRCC611669110823961 12519782 Affinity Capture-MS; Reconstituted Complex
NCOA6XRCC610882210823961 12519782 Affinity Capture-MS; Reconstituted Complex
NCOA6NR3C111669110567404 Reconstituted Complex
NCOA6NR3C110916510567404 Reconstituted Complex
NCOA6GTF2A110921210567404 Reconstituted Complex
NCOA6GTF2A111669110567404 Reconstituted Complex
NCOA6HNF4A11669118552123 Reconstituted Complex
NCOA6HNF4A10941418552123 Reconstituted Complex
NCOA6HSF110953014960326 Affinity Capture-Western; Co-localization
NCOA6HSF111669114960326 Affinity Capture-Western; Co-localization
NCOA6JUN10992810847592 Reconstituted Complex
NCOA6JUN11669110847592 Reconstituted Complex
NCOA6NFKB111085710847592 Reconstituted Complex
NCOA6NFKB111669110847592 Reconstituted Complex
NCOA6NUMA111669112519782 Affinity Capture-MS
NCOA6NUMA111098012519782 Affinity Capture-MS
NCOA6PRKDC11157710823961 Affinity Capture-MS; Biochemical Activity
NCOA6PRKDC11669110823961 Affinity Capture-MS; Biochemical Activity
NCOA6RARA11669110567404 10823961 11158331 Reconstituted Complex; Two-hybrid
NCOA6RARA11184910567404 10823961 11158331 Reconstituted Complex; Two-hybrid
NCOA6RB111669114645241 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6RB111186014645241 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6RBBP511669112482968 17500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NCOA6RBBP511186412482968 17500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NCOA6RELA11669110847592 Reconstituted Complex
NCOA6RELA11190210847592 Reconstituted Complex
NCOA6RXRA11216810567404 11158331 11773444 14578865 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6RXRA11669110567404 11158331 11773444 14578865 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6SRC11259210567404 10847592 11158331 12482968 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6SRC11669110567404 10847592 11158331 12482968 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6SRF11260010847592 Reconstituted Complex
NCOA6SRF11669110847592 Reconstituted Complex
NCOA6TBP11277110567404 Reconstituted Complex
NCOA6TBP11669110567404 Reconstituted Complex
NCOA6THRA11292310567404 10847592 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6THRA11669110567404 10847592 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6THRB11669110567404 10823961 11158331 11773444 Reconstituted Complex; Two-hybrid
NCOA6THRB11292410567404 10823961 11158331 11773444 Reconstituted Complex; Two-hybrid
NCOA6TUBA4A11312812482968 Affinity Capture-MS; Co-purification
NCOA6TUBA4A11669112482968 Affinity Capture-MS; Co-purification
NCOA6NR1H211669111158331 Reconstituted Complex; Two-hybrid
NCOA6NR1H211322211158331 Reconstituted Complex; Two-hybrid
NCOA6KDM6A11324617761849 19047629 Affinity Capture-MS
NCOA6KDM6A11669117761849 19047629 Affinity Capture-MS
NCOA6UTY11324719047629 Affinity Capture-MS
NCOA6UTY11669119047629 Affinity Capture-MS
NCOA6XRCC511335310823961 12519782 Affinity Capture-MS
NCOA6XRCC511669110823961 12519782 Affinity Capture-MS
NCOA6ASH2L11452817500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6ASH2L11669117500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6MED2311482910823961 Affinity Capture-Western
NCOA6MED2311669110823961 Affinity Capture-Western
NCOA6NCOR211669111158331 Two-hybrid
NCOA6NCOR211497411158331 Two-hybrid
NCOA6MLL411510417021013 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6MLL411669117021013 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6HBXIP11579614578865 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6HBXIP11669114578865 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA6TXNRD211669111158331 Reconstituted Complex; Two-hybrid
NCOA6TXNRD211583611158331 Reconstituted Complex; Two-hybrid
NCOA6PPARGC1A11609718552123 Reconstituted Complex
NCOA6PPARGC1A11669118552123 Reconstituted Complex
NCOA6WDR511627217021013 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6WDR511669117021013 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western
NCOA6PAXIP111662517500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NCOA6PAXIP111669117500065 17925232 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
ASCC1NCOA611921510567404 Reconstituted Complex
ASCC1NCOA611669110567404 Reconstituted Complex
TGS1NCOA612517911517327 11912212 12754253 Affinity Capture-Western; Reconstituted Complex
TGS1NCOA611669111517327 11912212 12754253 Affinity Capture-Western; Reconstituted Complex
ZNF335NCOA612199412215545 Reconstituted Complex; Two-hybrid
ZNF335NCOA611669112215545 Reconstituted Complex; Two-hybrid
MLL3NCOA612183512482968 17021013 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MLL3NCOA611669112482968 17021013 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
TUBBNCOA612844412482968 Affinity Capture-MS; Co-purification
TUBBNCOA611669112482968 Affinity Capture-MS; Co-purification
HIST2H3CNCOA612602512482968 Affinity Capture-Western; Reconstituted Complex
HIST2H3CNCOA611669112482968 Affinity Capture-Western; Reconstituted Complex
NCOA6NCOA611669117500065 Affinity Capture-Western
C16orf53NCOA612267217500065 Affinity Capture-Western
C16orf53NCOA611669117500065 Affinity Capture-Western
DPY30NCOA612418119047629 Affinity Capture-MS
DPY30NCOA611669119047629 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1929915
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080403-12'