AutismKB 2.0

Annotation Details for ERC1


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Basic Information Top
Gene Symbol:ERC1 ( Cast2,ELKS,FLJ31750,KIAA1081,MGC12974,RAB6IP2 )
Gene Full Name: ELKS/RAB6-interacting/CAST family member 1
Band: 12p13.33
Quick LinksEntrez ID:23085; OMIM: 607127; Uniprot ID:RB6I2_HUMAN; ENSEMBL ID: ENSG00000082805; HGNC ID: 17072
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005737ISS-cytoplasm-
GO:0005737TAS-cytoplasm15218148
GO:0008385IDA-IkappaB kinase complex15218148
GO:0042734TAS-presynaptic membrane12391317
GO:0045202ISS-synapse-
GO:0048786IEA-presynaptic active zone-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12391317
GO:0017137ISS-Rab GTPase binding-
GO:0030165ISS-PDZ domain binding-
GO:0043522NAS-leucine zipper domain binding15218148
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0006355NAS-regulation of transcription, DNA-templated15218148
GO:0007252IDA-I-kappaB phosphorylation15218148
GO:0007275NAS-multicellular organism development15218148
GO:0015031IEA-protein transport-
GO:0042147ISS-retrograde transport, endosome to Golgi-
GO:0043066TAS-negative regulation of apoptotic process15218148
GO:0051092TAS-positive regulation of NF-kappaB transcription factor activity15218148
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ERC1RAB6A11671411929610 Reconstituted Complex; Two-hybrid
ERC1RAB6A11180811929610 Reconstituted Complex; Two-hybrid
ERC1YWHAG11671417353931 Affinity Capture-MS
ERC1YWHAG11336417353931 Affinity Capture-MS
ERC1TWF211671417353931 Affinity Capture-MS
ERC1TWF211647217353931 Affinity Capture-MS
RAB6BERC111961011929610 Reconstituted Complex
RAB6BERC111671411929610 Reconstituted Complex
KBTBD7ERC111671420562859 Affinity Capture-MS
KBTBD7ERC112387320562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2151013
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041210-51'