AutismKB 2.0

Annotation Details for SIPA1L3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SIPA1L3 ( SPAL3 )
Gene Full Name: signal-induced proliferation-associated 1 like 3
Band: 19q13.13-q13.2
Quick LinksEntrez ID:23094; OMIM: NA; Uniprot ID:SI1L3_HUMAN; ENSEMBL ID: ENSG00000105738; HGNC ID: 23801
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IDA-stress fiber26231217
GO:0005615IDA-extracellular space22664934
GO:0016324IEA-apical plasma membrane-
GO:0045177IMP-apical part of cell26231217
GO:0061689IDA-tricellular tight junction26231217
GO ID Evidence Qualifier GO_term References
GO:0005096IEA-GTPase activator activity-
GO ID Evidence Qualifier GO_term References
GO:0001654ISS-eye development-
GO:0002244IEA-hematopoietic progenitor cell differentiation-
GO:0003382IDA-epithelial cell morphogenesis26231217
GO:0007010ISS-cytoskeleton organization-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056IEA-regulation of small GTPase mediated signal transduction-
GO:0090162IDA-establishment of epithelial cell polarity26231217
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SIPA1L3SFN11672215778465 Affinity Capture-MS
SIPA1L3SFN10907215778465 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SIPA1L3D19S220 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1921456
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018