AutismKB 2.0

Annotation Details for NFASC


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Basic Information Top
Gene Symbol:NFASC ( DKFZp686P2250,FLJ46866,KIAA0756,NF,NRCAML )
Gene Full Name: neurofascin
Band: 1q32.1
Quick LinksEntrez ID:23114; OMIM: 609145; Uniprot ID:NFASC_HUMAN; ENSEMBL ID: ENSG00000163531; HGNC ID: 29866
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622ISS-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0016021IEA-integral component of membrane-
GO:0033010IEA-paranodal junction-
GO:0033268ISS-node of Ranvier-
GO:0033268TAS-node of Ranvier16652168
GO:0033270IEA-paranode region of axon-
GO:0043194ISS-axon initial segment-
GO:0043209IEA-myelin sheath-
GO:0070062IDA-extracellular exosome23376485
GO:0097454IEA-Schwann cell microvillus-
GO:0101003TAS-ficolin-1-rich granule membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding23897819
GO:0019904IEA-protein domain specific binding-
GO:0086080IEA-protein binding involved in heterotypic cell-cell adhesion-
GO ID Evidence Qualifier GO_term References
GO:0002175IEA-protein localization to paranode region of axon-
GO:0007411IEA-axon guidance-
GO:0007422ISS-peripheral nervous system development-
GO:0019226IEA-transmission of nerve impulse-
GO:0030913IEA-paranodal junction assembly-
GO:0034113IEA-heterotypic cell-cell adhesion-
GO:0042552ISS-myelination-
GO:0043312TAS-neutrophil degranulation-
GO:0045162IEA-clustering of voltage-gated sodium channels-
GO:0050808IEA-synapse organization-
GO:0071205IEA-protein localization to juxtaparanode region of axon-
GO:0072661IEA-protein targeting to plasma membrane-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104753
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080229-6'