Annotation Details for RTF1

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Basic Information Top

Gene Symbol:	RTF1 ( GTL7,KIAA0252 )
Gene Full Name:	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Band:	15q15.1
Quick Links	Entrez ID:23168; OMIM: 611633; Uniprot ID:RTF1_HUMAN; ENSEMBL ID: ENSG00000137815; HGNC ID: 28996
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:5 results
Biological Process:12 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005654	TAS	-	nucleoplasm	-
GO:0005730	IEA	-	nucleolus	-
GO:0016593	IDA	-	Cdc73/Paf1 complex	20178742

GO ID	Evidence	Qualifier	GO_term	References
GO:0001076	IBA	-	transcription factor activity, RNA polymerase II transcription factor binding	-
GO:0003697	IDA	-	single-stranded DNA binding	18184592
GO:0003723	IDA	-	RNA binding	22658674
GO:0005515	IPI	-	protein binding	15923622
GO:1990269	IBA	-	RNA polymerase II C-terminal domain phosphoserine binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000122	ISS	-	negative regulation of transcription from RNA polymerase II promoter	-
GO:0001711	ISS	-	endodermal cell fate commitment	-
GO:0001832	IEA	-	blastocyst growth	-
GO:0006366	TAS	-	transcription from RNA polymerase II promoter	-
GO:0006368	TAS	-	transcription elongation from RNA polymerase II promoter	-
GO:0016055	IEA	-	Wnt signaling pathway	-
GO:0016567	TAS	-	protein ubiquitination	-
GO:0019827	IDA	-	stem cell population maintenance	19345177
GO:0032968	IDA	-	positive regulation of transcription elongation from RNA polymerase II promoter	20178742
GO:0045944	IDA	-	positive regulation of transcription from RNA polymerase II promoter	20178742
GO:0051571	IEA	-	positive regulation of histone H3-K4 methylation	-
GO:0080182	IEA	-	histone H3-K4 trimethylation	-

Protein-Protein Interaction

BioGRID:8 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
RTF1	ARRB1	116780	17353931	Affinity Capture-MS
RTF1	ARRB1	106901	17353931	Affinity Capture-MS
RTF1	CTR9	116780	18469135	Affinity Capture-MS
RTF1	CTR9	115004	18469135	Affinity Capture-MS
LEO1	RTF1	125817	18469135	Affinity Capture-MS
LEO1	RTF1	116780	18469135	Affinity Capture-MS
PAF1	RTF1	120081	18469135	Affinity Capture-MS; Affinity Capture-Western
PAF1	RTF1	116780	18469135	Affinity Capture-MS; Affinity Capture-Western

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1309480
Data Attributes: HomoloGene calculated