AutismKB 2.0

Annotation Details for FLOT2


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Basic Information Top
Gene Symbol:FLOT2 ( ECS-1,ECS1,ESA,ESA1,M17S1 )
Gene Full Name: flotillin 2
Band: 17q11.2
Quick LinksEntrez ID:2319; OMIM: 131560; Uniprot ID:FLOT2_HUMAN; ENSEMBL ID: ENSG00000132589; HGNC ID: 3758
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001931IDA-uropod21696602
GO:0002080IEA-acrosomal membrane-
GO:0005768IDA-endosome20682791
GO:0005886IMP-plasma membrane21696602
GO:0005886TAS-plasma membrane-
GO:0005901IDA-caveola24013648
GO:0005913IDA-cell-cell adherens junction24046456
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane19946888
GO:0016323IDA-basolateral plasma membrane23983584
GO:0016324IDANOTapical plasma membrane23983584
GO:0016600IDA-flotillin complex21696602
GO:0030027IDA-lamellipodium24046456
GO:0030139IDA-endocytic vesicle20682791
GO:0030864IDAcolocalizes_withcortical actin cytoskeleton24046456
GO:0031410IDA-cytoplasmic vesicle23983584
GO:0031982IDA-vesicle21119006
GO:0044291IDA-cell-cell contact zone23983584
GO:0048471IDA-perinuclear region of cytoplasm21119006
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0002020IEA-protease binding-
GO:0005515IPI-protein binding17113085
GO:0035255IEA-ionotropic glutamate receptor binding-
GO:0046982IMP-protein heterodimerization activity21696602
GO ID Evidence Qualifier GO_term References
GO:0001765IMP-membrane raft assembly25204797
GO:0007155IEA-cell adhesion-
GO:0008544TAS-epidermis development8051082
GO:0010629IMP-negative regulation of gene expression24612608
GO:0034114IMPNOTregulation of heterotypic cell-cell adhesion25204797
GO:0034139IMPNOTregulation of toll-like receptor 3 signaling pathway25204797
GO:0044860IMP-protein localization to plasma membrane raft21696602
GO:0045661IEP-regulation of myoblast differentiation25105415
GO:0050821IMP-protein stabilization24612608
GO:0090002IMP-establishment of protein localization to plasma membrane24612608
GO:1902992IMP-negative regulation of amyloid precursor protein catabolic process24612608
GO:1903905IMP-positive regulation of establishment of T cell polarity21696602
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FLOT2CAV110730510212252 Affinity Capture-Western
FLOT2CAV110860810212252 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103309
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020430-3'