AutismKB 2.0

Annotation Details for PSME4


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Basic Information Top
Gene Symbol:PSME4 ( FLJ21864,KIAA0077,MGC138374,MGC142228,PA200 )
Gene Full Name: proteasome (prosome, macropain) activator subunit 4
Band: 2p16.2
Quick LinksEntrez ID:23198; OMIM: 607705; Uniprot ID:PSME4_HUMAN; ENSEMBL ID: ENSG00000068878; HGNC ID: 20635
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21630459
GO:0005634ISS-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005829IBA-cytosol-
GO:0005829ISS-cytosol-
GO:0005829TAS-cytosol-
GO:0005839IBA-proteasome core complex-
GO:0016607IEA-nuclear speck-
GO:1990111IBA-spermatoproteasome complex-
GO:1990111ISS-spermatoproteasome complex-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0016504IBA-peptidase activator activity-
GO:0016504ISS-peptidase activator activity-
GO:0070577IBA-lysine-acetylated histone binding-
GO:0070577ISS-lysine-acetylated histone binding-
GO:0070628IBA-proteasome binding-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006281ISS-DNA repair-
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0006974ISS-cellular response to DNA damage stimulus-
GO:0007275IEA-multicellular organism development-
GO:0010499IBA-proteasomal ubiquitin-independent protein catabolic process-
GO:0010499ISS-proteasomal ubiquitin-independent protein catabolic process-
GO:0010952IEA-positive regulation of peptidase activity-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0035093IBA-spermatogenesis, exchange of chromosomal proteins-
GO:0035093ISS-spermatogenesis, exchange of chromosomal proteins-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2143994
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-091204-452'