AutismKB 2.0

Annotation Details for SYNE2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SYNE2 ( DKFZp434H2235,DKFZp686E01115,DKFZp686H1931,EDMD5,FLJ11014,FLJ43727,FLJ45710,FLJ46790,KIAA1011,NUA,NUANCE,Nesprin-2,SYNE-2,TROPH )
Gene Full Name: spectrin repeat containing, nuclear envelope 2
Band: 14q23.2
Quick LinksEntrez ID:23224; OMIM: 608442; Uniprot ID:SYNE2_HUMAN; ENSEMBL ID: ENSG00000054654; HGNC ID: 17084
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12118075
GO:0005635IDA-nuclear envelope15671068
GO:0005640IEA-nuclear outer membrane-
GO:0005654IEA-nucleoplasm-
GO:0005737IDA-cytoplasm12118075
GO:0005739IDA-mitochondrion15671068
GO:0005925IDA-focal adhesion15671068
GO:0016021IEA-integral component of membrane-
GO:0016235IDA-aggresome-
GO:0016529IDA-sarcoplasmic reticulum15671068
GO:0030018IDA-Z disc15671068
GO:0031258IDA-lamellipodium membrane15671068
GO:0031527IDA-filopodium membrane15671068
GO:0031965IDA-nuclear membrane-
GO:0031981IDA-nuclear lumen15671068
GO:0033017IEA-sarcoplasmic reticulum membrane-
GO:0034993IDA-LINC complex18396275
GO:0045111IDA-intermediate filament cytoskeleton-
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0003779ISS-actin binding-
GO:0005515IPI-protein binding15671068
GO:0051015IEA-actin filament binding-
GO ID Evidence Qualifier GO_term References
GO:0006998IEA-nuclear envelope organization-
GO:0007097IMP-nuclear migration20724637
GO:0007163IEA-establishment or maintenance of cell polarity-
GO:0010761IEA-fibroblast migration-
GO:0021817IEA-nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration-
GO:0030335ISS-positive regulation of cell migration-
GO:0031022ISS-nuclear migration along microfilament-
GO:0034504IEA-protein localization to nucleus-
GO:0051642IMP-centrosome localization20724637
GO:0090286IDA-cytoskeletal anchoring at nuclear membrane18396275
GO:1902017IEA-regulation of cilium assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SYNE2ACTC110658512118075 Reconstituted Complex
SYNE2ACTC111683012118075 Reconstituted Complex
C20orf94SYNE212614719596235 Affinity Capture-MS
C20orf94SYNE211683019596235 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2449316
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041001-109'