AutismKB 2.0

Annotation Details for PHLPP1


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Basic Information Top
Gene Symbol:PHLPP1 ( MGC161555,PHLPP,PLEKHE1,SCOP )
Gene Full Name: PH domain and leucine rich repeat protein phosphatase 1
Band: 18q21.33
Quick LinksEntrez ID:23239; OMIM: 609396; Uniprot ID:PHLP1_HUMAN; ENSEMBL ID: ENSG00000081913; HGNC ID: 20610
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO:0005886IBA-plasma membrane-
GO:0031965IBA-nuclear membrane-
GO ID Evidence Qualifier GO_term References
GO:0004722IBA-protein serine/threonine phosphatase activity-
GO:0005515IPI-protein binding18162466
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0002667IEA-regulation of T cell anergy-
GO:0006470IEA-protein dephosphorylation-
GO:0006915IEA-apoptotic process-
GO:0009649IEA-entrainment of circadian clock-
GO:0042981IDA-regulation of apoptotic process20513427
GO:0043408IMP-regulation of MAPK cascade24530606
GO:0046328IDA-regulation of JNK cascade17386267
GO:0051898IMP-negative regulation of protein kinase B signaling17386267
GO:0090036IBA-regulation of protein kinase C signaling-
GO:1900744IDA-regulation of p38MAPK cascade17386267
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PHLPP1CSNK1A111684319797085 Biochemical Activity
PHLPP1CSNK1A110783619797085 Biochemical Activity
PHLPP1DMWD10810219615732 Affinity Capture-MS
PHLPP1DMWD11684319615732 Affinity Capture-MS
PHLPP1MARK211684319615732 Affinity Capture-MS
PHLPP1MARK210832619615732 Affinity Capture-MS
PHLPP1FKBP511684319615732 Affinity Capture-MS
PHLPP1FKBP510857919615732 Affinity Capture-MS
PHLPP1GSK3B11684319797085 Biochemical Activity
PHLPP1GSK3B10918719797085 Biochemical Activity
PHLPP1PPP5C11152819615732 Affinity Capture-MS
PHLPP1PPP5C11684319615732 Affinity Capture-MS
PHLPP1UBC11684319797085 Affinity Capture-Western
PHLPP1UBC11316419797085 Affinity Capture-Western
PHLPP1USP111324119615732 Affinity Capture-MS
PHLPP1USP111684319615732 Affinity Capture-MS
PHLPP1BTRC11684319797085 Affinity Capture-Western
PHLPP1BTRC11445719797085 Affinity Capture-Western
PHLPP1SLC9A3R211684319615732 Affinity Capture-MS
PHLPP1SLC9A3R211475419615732 Affinity Capture-MS
PHLPP1SUGT111684319615732 Affinity Capture-MS
PHLPP1SUGT111611519615732 Affinity Capture-MS
PHLPP1PHLPP211684319615732 Affinity Capture-MS
PHLPP1PHLPP211667419615732 Affinity Capture-MS
USP12PHLPP111684319615732 Affinity Capture-MS
USP12PHLPP112852219615732 Affinity Capture-MS
SCRIBPHLPP111684319615732 Affinity Capture-MS
SCRIBPHLPP111706019615732 Affinity Capture-MS
WDR48PHLPP112164919615732 Affinity Capture-MS
WDR48PHLPP111684319615732 Affinity Capture-MS
RBM15PHLPP112229319615732 Affinity Capture-MS
RBM15PHLPP111684319615732 Affinity Capture-MS
USP46PHLPP112232719615732 Affinity Capture-MS
USP46PHLPP111684319615732 Affinity Capture-MS
SNX27PHLPP111684319615732 Affinity Capture-MS
SNX27PHLPP112354619615732 Affinity Capture-MS
WDR20PHLPP111684319615732 Affinity Capture-MS
WDR20PHLPP112488419615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2138327
  • Data Attributes: HomoloGene calculated
No data