AutismKB 2.0

Annotation Details for FBXW11


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Basic Information Top
Gene Symbol:FBXW11 ( BTRC2,BTRCP2,FBW1B,FBXW1B,Fbw11,Hos,KIAA0696 )
Gene Full Name: F-box and WD repeat domain containing 11
Band: 5q35.1
Quick LinksEntrez ID:23291; OMIM: 605651; Uniprot ID:FBW1B_HUMAN; ENSEMBL ID: ENSG00000072803; HGNC ID: 13607
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000151NAS-ubiquitin ligase complex10531035
GO:0005634ISS-nucleus-
GO:0005813IDA-centrosome21399614
GO:0005829ISS-cytosol-
GO:0005829TAS-cytosol-
GO:0019005IDA-SCF ubiquitin ligase complex16880511
GO ID Evidence Qualifier GO_term References
GO:0004842EXP-ubiquitin-protein transferase activity11158290
GO:0004842IDA-ubiquitin-protein transferase activity20347421
GO:0004842NAS-ubiquitin-protein transferase activity10531035
GO:0004842TAS-ubiquitin-protein transferase activity-
GO:0005515IPI-protein binding12482991
GO:0046983IEA-protein dimerization activity-
GO:0061630IEA-ubiquitin protein ligase activity-
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0000209IDA-protein polyubiquitination20347421
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0006470ISS-protein dephosphorylation-
GO:0016055IEA-Wnt signaling pathway-
GO:0016567IDA-protein ubiquitination16885022
GO:0016567NAS-protein ubiquitination10531035
GO:0031146IDA-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process20347421
GO:0031648IMP-protein destabilization16885022
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0042347IEA-negative regulation of NF-kappaB import into nucleus-
GO:0042753ISS-positive regulation of circadian rhythm-
GO:0043161IDA-proteasome-mediated ubiquitin-dependent protein catabolic process20347421
GO:0043687TAS-post-translational protein modification-
GO:0045862IMP-positive regulation of proteolysis16885022
GO:0045892IMP-negative regulation of transcription, DNA-templated19966869
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0048511IEA-rhythmic process-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051403TAS-stress-activated MAPK cascade-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FBXW11CDC25A10742814681206 15798217 Affinity Capture-Western; Reconstituted Complex
FBXW11CDC25A11688714681206 15798217 Affinity Capture-Western; Reconstituted Complex
FBXW11CDC25B10742919615732 Affinity Capture-MS
FBXW11CDC25B11688719615732 Affinity Capture-MS
FBXW11CTNNB110788016085715 Affinity Capture-Western
FBXW11CTNNB111688716085715 Affinity Capture-Western
FBXW11HIVEP110934319615732 Affinity Capture-MS
FBXW11HIVEP111688719615732 Affinity Capture-MS
FBXW11HIVEP210934419615732 Affinity Capture-MS
FBXW11HIVEP211688719615732 Affinity Capture-MS
FBXW11IFNAR110967614532120 15337770 Affinity Capture-Western; Biochemical Activity; Protein-peptide; Reconstituted Complex
FBXW11IFNAR111688714532120 15337770 Affinity Capture-Western; Biochemical Activity; Protein-peptide; Reconstituted Complex
FBXW11MYO1011073519615732 Affinity Capture-MS
FBXW11MYO1011688719615732 Affinity Capture-MS
FBXW11NFKBIA11085910644755 Affinity Capture-Western
FBXW11NFKBIA11688710644755 Affinity Capture-Western
FBXW11NRD111095419615732 Affinity Capture-MS
FBXW11NRD111688719615732 Affinity Capture-MS
FBXW11PER111121015917222 Affinity Capture-Western; Reconstituted Complex
FBXW11PER111688715917222 Affinity Capture-Western; Reconstituted Complex
FBXW11PRLR11160315082796 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
FBXW11PRLR11688715082796 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
FBXW11SKP111688710644755 15070733 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11SKP111239110644755 15070733 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11TRIM2111688716880511 Affinity Capture-Western; Reconstituted Complex
FBXW11TRIM2111261516880511 Affinity Capture-Western; Reconstituted Complex
FBXW11TFAP411688719615732 Affinity Capture-MS
FBXW11TFAP411288119615732 Affinity Capture-MS
FBXW11TNF11688715485837 Affinity Capture-MS
FBXW11TNF11297915485837 Affinity Capture-MS
FBXW11UBC11688714707120 Affinity Capture-Western
FBXW11UBC11316414707120 Affinity Capture-Western
FBXW11WEE111688715070733 16085715 Affinity Capture-Western
FBXW11WEE111330315070733 16085715 Affinity Capture-Western
FBXW11CUL111403210644755 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11CUL111688710644755 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11OGT11688719615732 Affinity Capture-MS
FBXW11OGT11404919615732 Affinity Capture-MS
FBXW11BTRC11688710644755 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11BTRC11445710644755 19615732 Affinity Capture-MS; Affinity Capture-Western
FBXW11TUBGCP311688719615732 Affinity Capture-MS
FBXW11TUBGCP311569519615732 Affinity Capture-MS
FBXW11NUDC11688719615732 Affinity Capture-MS
FBXW11NUDC11595019615732 Affinity Capture-MS
FBXW11CLPX11688719615732 Affinity Capture-MS
FBXW11CLPX11605619615732 Affinity Capture-MS
FBXW11ATG4B11688719615732 Affinity Capture-MS
FBXW11ATG4B11680119615732 Affinity Capture-MS
FBXW11FBXW1111688710644755 Affinity Capture-Western
CLSPNFBXW1111688716885022 Affinity Capture-Western
CLSPNFBXW1112201516885022 Affinity Capture-Western
RPRMFBXW1111688717353931 Affinity Capture-MS
RPRMFBXW1112114517353931 Affinity Capture-MS
FAM123BFBXW1112655617510365 Reconstituted Complex
FAM123BFBXW1111688717510365 Reconstituted Complex
KHDRBS2FBXW1111688717643375 Affinity Capture-MS
KHDRBS2FBXW1112843617643375 Affinity Capture-MS
SUN2FBXW1111688719615732 Affinity Capture-MS
SUN2FBXW1111731219615732 Affinity Capture-MS
ARIH1FBXW1111688719615732 Affinity Capture-MS
ARIH1FBXW1111734819615732 Affinity Capture-MS
PDCD4FBXW1111688719615732 Affinity Capture-MS
PDCD4FBXW1111809819615732 Affinity Capture-MS
ZRANB1FBXW1111688719615732 Affinity Capture-MS
ZRANB1FBXW1112013919615732 Affinity Capture-MS
USP47FBXW1111688719615732 Affinity Capture-MS
USP47FBXW1112036019615732 Affinity Capture-MS
USP37FBXW1111688719615732 Affinity Capture-MS
USP37FBXW1112172019615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2144023
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6305'