AutismKB 2.0

Annotation Details for UBR2


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Basic Information Top
Gene Symbol:UBR2 ( C6orf133,DKFZp686C08114,FLJ36357,KIAA0349,MGC71112,RP3-392M17.3,bA49A4.1,dJ242G1.1,dJ392M17.3 )
Gene Full Name: ubiquitin protein ligase E3 component n-recognin 2
Band: 6p21.1
Quick LinksEntrez ID:23304; OMIM: 609134; Uniprot ID:UBR2_HUMAN; ENSEMBL ID: ENSG00000024048; HGNC ID: 21289
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000151IBA-ubiquitin ligase complex-
GO:0000785IEA-chromatin-
GO:0005634IEA-nucleus-
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004842EXP-ubiquitin-protein transferase activity19028597
GO:0004842TAS-ubiquitin-protein transferase activity-
GO:0005515IPI-protein binding22190034
GO:0008270IEA-zinc ion binding-
GO:0061630IBA-ubiquitin protein ligase activity-
GO:0070728IDA-leucine binding20298436
GO ID Evidence Qualifier GO_term References
GO:0000209TAS-protein polyubiquitination-
GO:0006342IBA-chromatin silencing-
GO:0006342ISS-chromatin silencing-
GO:0007141IEA-male meiosis I-
GO:0007283IEA-spermatogenesis-
GO:0032007IMP-negative regulation of TOR signaling20298436
GO:0033522IBA-histone H2A ubiquitination-
GO:0033522ISS-histone H2A ubiquitination-
GO:0071233IDA-cellular response to leucine20298436
GO:0071596IBA-ubiquitin-dependent protein catabolic process via the N-end rule pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBR2HNRNPA111689617643375 Affinity Capture-MS
UBR2HNRNPA110942017643375 Affinity Capture-MS
UBR2UBE2B11689614585983 Affinity Capture-Western
UBR2UBE2B11316814585983 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1861099
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081107-29'