AutismKB 2.0

Annotation Details for AFF2


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Basic Information Top
Gene Symbol:AFF2 ( FMR2,FRAXE,MRX2,OX19 )
Gene Full Name: AF4/FMR2 family, member 2
Band: Xq28
Quick LinksEntrez ID:2334; OMIM: 300806; Uniprot ID:AFF2_HUMAN; ENSEMBL ID: ENSG00000155966; HGNC ID: 3776
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0016607IDA-nuclear speck19136466
GO ID Evidence Qualifier GO_term References
GO:0002151ISS-G-quadruplex RNA binding-
GO ID Evidence Qualifier GO_term References
GO:0006397IEA-mRNA processing-
GO:0007420TAS-brain development8673086
GO:0007611IEA-learning or memory-
GO:0008380IEA-RNA splicing-
GO:0010468IMP-regulation of gene expression23562910
GO:0010629IEA-negative regulation of gene expression-
GO:0035063IMP-nuclear speck organization23562910
GO:0043484IMP-regulation of RNA splicing19136466
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1202294
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018