AutismKB 2.0

Annotation Details for PUM2


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Basic Information Top
Gene Symbol:PUM2 ( FLJ36528,KIAA0235,MGC138251,MGC138253,PUMH2,PUML2 )
Gene Full Name: pumilio homolog 2 (Drosophila)
Band: 2p24.1
Quick LinksEntrez ID:23369; OMIM: 607205; Uniprot ID:PUM2_HUMAN; ENSEMBL ID: ENSG00000055917; HGNC ID: 14958
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol-
GO:0010494IDA-cytoplasmic stress granule25340845
GO:0010494ISS-cytoplasmic stress granule-
GO:0031965IDA-nuclear membrane-
GO:0048471IDA-perinuclear region of cytoplasm19168546
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003730IDA-mRNA 3'-UTR binding18776931
GO:0005515IPI-protein binding12511597
GO ID Evidence Qualifier GO_term References
GO:0010608IDA-posttranscriptional regulation of gene expression25100735
GO:0034063IEA-stress granule assembly-
GO:0043488IDA-regulation of mRNA stability26724866
GO:0051983IDA-regulation of chromosome segregation26724866
GO:0060964TAS-regulation of gene silencing by miRNA18776931
GO:1900246IDA-positive regulation of RIG-I signaling pathway25340845
GO:2000637IMP-positive regulation of gene silencing by miRNA22345517
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NANOS1PUM211694912690449 Affinity Capture-Western; Two-hybrid
NANOS1PUM213109212690449 Affinity Capture-Western; Two-hybrid
PUM2PUM211694912690449 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1931751
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018