AutismKB 2.0

Annotation Details for TENC1


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Basic Information Top
Gene Symbol:TENC1 ( C1-TEN,C1TEN,DKFZp686D13244,FLJ16320,KIAA1075,TNS2 )
Gene Full Name: tensin like C1 domain containing phosphatase (tensin 2)
Band: 12q13.13
Quick LinksEntrez ID:23371; OMIM: 607717; Uniprot ID:TENC1_HUMAN; ENSEMBL ID: ENSG00000111077; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886IEA-plasma membrane-
GO:0005925IDA-focal adhesion16951145
GO ID Evidence Qualifier GO_term References
GO:0004721IEA-phosphoprotein phosphatase activity-
GO:0005515IPI-protein binding16273093
GO:0019900IPI-kinase binding22019427
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001822IEA-kidney development-
GO:0006470IEA-protein dephosphorylation-
GO:0008285IMP-negative regulation of cell proliferation16951145
GO:0014850IEA-response to muscle activity-
GO:0019725IEA-cellular homeostasis-
GO:0032963IEA-collagen metabolic process-
GO:0035264IEA-multicellular organism growth-
GO:0035556IEA-intracellular signal transduction-
GO:0048871IEA-multicellular organismal homeostasis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TENC1AXL11695112470648 Affinity Capture-Western; Two-hybrid
TENC1AXL10703612470648 Affinity Capture-Western; Two-hybrid
Gene Symbol Interactant Interaction ID References Description
TENC1FGFR125965115117958 An unspecified isoform of FGFR1 interacts with KIAA1075. This interaction was modeled on a demonstrated interaction between FGFR1 from an unspecified species and human KIAA1075.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2387586
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090312-163'