AutismKB 2.0

Annotation Details for CRTC1


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Basic Information Top
Gene Symbol:CRTC1 ( FLJ14027,KIAA0616,MECT1,TORC1,WAMTP1 )
Gene Full Name: CREB regulated transcription coactivator 1
Band: 19p13.11
Quick LinksEntrez ID:23373; OMIM: 607536; Uniprot ID:CRTC1_HUMAN; ENSEMBL ID: ENSG00000105662; HGNC ID: 16062
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus14506290
GO:0005654IDA-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO:0016604IDA-nuclear body-
GO:0030425IEA-dendrite-
GO:0043025IEA-neuronal cell body-
GO:0045202IEA-synapse-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding14506290
GO:0008140IDA-cAMP response element binding protein binding14536081
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0007613IEA-memory-
GO:0016032IEA-viral process-
GO:0032793IBA-positive regulation of CREB transcription factor activity-
GO:0032793ISS-positive regulation of CREB transcription factor activity-
GO:0043153ISS-entrainment of circadian clock by photoperiod-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter14536081
GO:0048511IEA-rhythmic process-
GO:0051289IEA-protein homotetramerization-
GO:0097009IEA-energy homeostasis-
GO:1900006IEA-positive regulation of dendrite development-
GO:1900273IEA-positive regulation of long-term synaptic potentiation-
GO:1902631IEA-negative regulation of membrane hyperpolarization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CRTC1CREB111695220936779 Two-hybrid
CRTC1CREB110777520936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2142523
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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