AutismKB 2.0

Annotation Details for FNTA


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Basic Information Top
Gene Symbol:FNTA ( FPTA,MGC99680,PGGT1A,PTAR2 )
Gene Full Name: farnesyltransferase, CAAX box, alpha
Band: 8p11.21
Quick LinksEntrez ID:2339; OMIM: 134635; Uniprot ID:FNTA_HUMAN; ENSEMBL ID: ENSG00000168522; HGNC ID: 3782
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm8599089
GO:0005829TAS-cytosol-
GO:0005875IDA-microtubule associated complex19228685
GO:0005886IEA-plasma membrane-
GO:0005953IDA-CAAX-protein geranylgeranyltransferase complex16893176
GO:0005965IDA-protein farnesyltransferase complex16893176
GO ID Evidence Qualifier GO_term References
GO:0004660IDA-protein farnesyltransferase activity16893176
GO:0004660IDAcontributes_toprotein farnesyltransferase activity19228685
GO:0004661IDA-protein geranylgeranyltransferase activity16893176
GO:0004662IEA-CAAX-protein geranylgeranyltransferase activity-
GO:0004663IEA-Rab geranylgeranyltransferase activity-
GO:0005515IPI-protein binding11687658
GO:0008017IDA-microtubule binding19228685
GO:0030548IEA-acetylcholine receptor regulator activity-
GO:0030971IEA-receptor tyrosine kinase binding-
GO:0043014IDA-alpha-tubulin binding19228685
GO ID Evidence Qualifier GO_term References
GO:0007179TAS-transforming growth factor beta receptor signaling pathway8599089
GO:0018343IDA-protein farnesylation16893176
GO:0018344IDA-protein geranylgeranylation16893176
GO:0022400TAS-regulation of rhodopsin mediated signaling pathway-
GO:0045213IEA-neurotransmitter receptor metabolic process-
GO:0071340IEA-skeletal muscle acetylcholine-gated channel clustering-
GO:0090044IDA-positive regulation of tubulin deacetylation19228685
GO:0090045IDA-positive regulation of deacetylase activity19228685
GO:0097194TAS-execution phase of apoptosis-
GO:0099601IEA-regulation of neurotransmitter receptor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FNTAACVR11086258599089 Two-hybrid
FNTAACVR11066058599089 Two-hybrid
TGFBR1FNTA1086258530343 Biochemical Activity; Reconstituted Complex; Two-hybrid
TGFBR1FNTA1129048530343 Biochemical Activity; Reconstituted Complex; Two-hybrid
TGFB1FNTA1086258599089 Two-hybrid
TGFB1FNTA1128988599089 Two-hybrid
PTP4A2FNTA10862517353931 Affinity Capture-MS
PTP4A2FNTA11374717353931 Affinity Capture-MS
HDAC6FNTA11533019228685 Affinity Capture-Western; Reconstituted Complex
HDAC6FNTA10862519228685 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104683
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-866'