AutismKB 2.0

Annotation Details for ZFPM2


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Basic Information Top
Gene Symbol:ZFPM2 ( DIH3,FOG2,MGC129663,MGC129664,ZNF89B,hFOG-2 )
Gene Full Name: zinc finger protein, multitype 2
Band: 8q23
Quick LinksEntrez ID:23414; OMIM: 603693; Uniprot ID:FOG2_HUMAN; ENSEMBL ID: ENSG00000169946; HGNC ID: 16700
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0001078IBA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001085IBA-RNA polymerase II transcription factor binding-
GO:0001105NAS-RNA polymerase II transcription coactivator activity10438528
GO:0003677IEA-DNA binding-
GO:0003714IDA-transcription corepressor activity10438528
GO:0005515IPI-protein binding10438528
GO:0008134IPI-transcription factor binding10438528
GO:0008270NAS-zinc ion binding10438528
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0001570IEA-vasculogenesis-
GO:0001701IEA-in utero embryonic development-
GO:0003148IMP-outflow tract septum morphogenesis20807224
GO:0003221IMP-right ventricular cardiac muscle tissue morphogenesis20807224
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007506IEA-gonadal mesoderm development-
GO:0007596TAS-blood coagulation-
GO:0030324IEA-lung development-
GO:0045599IMP-negative regulation of fat cell differentiation20705609
GO:0045892IDA-negative regulation of transcription, DNA-templated20206639
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter10438528
GO:0048568IEA-embryonic organ development-
GO:0060045IEA-positive regulation of cardiac muscle cell proliferation-
GO:0060412IMP-ventricular septum morphogenesis20807224
GO:0060548IEA-negative regulation of cell death-
GO:2000020IEA-positive regulation of male gonad development-
GO:2000195IEA-negative regulation of female gonad development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZFPM2CTBP210787010438528 Reconstituted Complex; Two-hybrid
ZFPM2CTBP211698610438528 Reconstituted Complex; Two-hybrid
ZFPM2GATA110889310438528 Reconstituted Complex; Two-hybrid
ZFPM2GATA111698610438528 Reconstituted Complex; Two-hybrid
ZFPM2GATA41088969927675 18252717 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZFPM2GATA41169869927675 18252717 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZFPM2HDAC110931518067919 Affinity Capture-MS
ZFPM2HDAC111698618067919 Affinity Capture-MS
ZFPM2HDAC210931618067919 Affinity Capture-MS
ZFPM2HDAC211698618067919 Affinity Capture-MS
ZFPM2RBBP411186318067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2RBBP411698618067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2RBBP711186618067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2RBBP711698618067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2MTA111456218067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2MTA111698618067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2MTA211465218067919 Affinity Capture-MS; Affinity Capture-Western
ZFPM2MTA211698618067919 Affinity Capture-MS; Affinity Capture-Western
MTA3ZFPM212156818067919 Affinity Capture-Western
MTA3ZFPM211698618067919 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1334444
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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