AutismKB 2.0

Annotation Details for SLC7A8


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Basic Information Top
Gene Symbol:SLC7A8 ( LAT2,LPI-PC1 )
Gene Full Name: solute carrier family 7 (amino acid transporter, L-type), member 8
Band: 14q11.2
Quick LinksEntrez ID:23428; OMIM: 604235; Uniprot ID:LAT2_HUMAN; ENSEMBL ID: ENSG00000092068; HGNC ID: 11066
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005886IDA-plasma membrane10391915
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane10391915
GO:0016323IEA-basolateral plasma membrane-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12716892
GO:0015101IDA-organic cation transmembrane transporter activity12117417
GO:0015171EXP-amino acid transmembrane transporter activity10391915
GO:0015171IDA-amino acid transmembrane transporter activity10391915
GO:0015171ISS-amino acid transmembrane transporter activity-
GO:0015175TAS-neutral amino acid transmembrane transporter activity10391915
GO:0015179IBA-L-amino acid transmembrane transporter activity-
GO:0015297IBA-antiporter activity-
GO:0019534IDA-toxin transporter activity12117417
GO:0042605ISS-peptide antigen binding-
GO ID Evidence Qualifier GO_term References
GO:0006520TAS-cellular amino acid metabolic process10391915
GO:0006810TAS-transport10391915
GO:0006865IDA-amino acid transport10391915
GO:0006865TAS-amino acid transport-
GO:0009636NAS-response to toxic substance11311135
GO:0015695IEA-organic cation transport-
GO:0015804ISS-neutral amino acid transport-
GO:0050900TAS-leukocyte migration-
GO:0055065NAS-metal ion homeostasis11311135
GO:1901998IEA-toxin transport-
GO:1902475IEA-L-alpha-amino acid transmembrane transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SLC7A8BAAT10704610574970 Affinity Capture-Western
SLC7A8BAAT11699610574970 Affinity Capture-Western
SLC7A8SLC3A211241110574970 Affinity Capture-Western
SLC7A8SLC3A211699610574970 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1355323
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030616-586'