AutismKB 2.0

Annotation Details for MACF1


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Basic Information Top
Gene Symbol:MACF1 ( ABP620,ACF7,FLJ45612,FLJ46776,KIAA0465,KIAA1251,MACF,OFC4 )
Gene Full Name: microtubule-actin crosslinking factor 1
Band: 1p34.3
Quick LinksEntrez ID:23499; OMIM: 608271; Uniprot ID:MACF1_HUMAN; ENSEMBL ID: ENSG00000127603; HGNC ID: 13664
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10559237
GO:0005737ISS-cytoplasm-
GO:0005794IDA-Golgi apparatus15265687
GO:0005856NAS-cytoskeleton10529403
GO:0005874IDA-microtubule16076900
GO:0005886IDA-plasma membrane20937854
GO:0032587IDA-ruffle membrane20937854
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22681889
GO:0003779IDA-actin binding10559237
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding11443112
GO:0008017IEA-microtubule binding-
GO:0016887ISS-ATPase activity-
GO:0045296IDA-cadherin binding25468996
GO:0051015NAS-actin filament binding10529403
GO ID Evidence Qualifier GO_term References
GO:0010632ISS-regulation of epithelial cell migration-
GO:0016055IEA-Wnt signaling pathway-
GO:0030177ISS-positive regulation of Wnt signaling pathway-
GO:0032886IMP-regulation of microtubule-based process20937854
GO:0042060ISS-wound healing-
GO:0043001IDA-Golgi to plasma membrane protein transport15265687
GO:0045773IDA-positive regulation of axon extension22705394
GO:0051893ISS-regulation of focal adhesion assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MACF1APC10682120936779 Two-hybrid
MACF1APC11704820936779 Two-hybrid
MACF1JUN10992820936779 Two-hybrid
MACF1JUN11704820936779 Two-hybrid
MACF1MAPK911704820936779 Two-hybrid
MACF1MAPK911158720936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108559
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3606'