AutismKB 2.0

Annotation Details for PRAME


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Basic Information Top
Gene Symbol:PRAME ( CT130,MAPE,OIP4 )
Gene Full Name: preferentially expressed antigen in melanoma
Band: 22q11.22
Quick LinksEntrez ID:23532; OMIM: 606021; Uniprot ID:PRAME_HUMAN; ENSEMBL ID: ENSG00000185686; HGNC ID: 9336
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005886IEA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16179254
GO:0042974IDA-retinoic acid receptor binding16179254
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006915IEA-apoptotic process-
GO:0008284IDA-positive regulation of cell proliferation16179254
GO:0030154IEA-cell differentiation-
GO:0040008IEA-regulation of growth-
GO:0043066IDA-negative regulation of apoptotic process16179254
GO:0045596IDA-negative regulation of cell differentiation16179254
GO:0045892IDA-negative regulation of transcription, DNA-templated16179254
GO:0048387IDA-negative regulation of retinoic acid receptor signaling pathway16179254
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRAMESTK1911438314667819 Two-hybrid
PRAMESTK1911707814667819 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018